Evidence map›Paper›PMID 35416493›Full record

ArticleUrolithiasis2022

Differences in renal cortex transcriptional profiling of wild-type and novel type B cystinuria model rats.

Zihan Zhang, Rui Zheng, Zhoutong Chen, Xia Zhan, Xiaoliang Fang, Meizhen Liu, Yongmei Li, Yonghu Xu, Dali Li, Hongquan Geng and 2 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Urolithiasis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Zihan ZhangDepartment of Pediatric Urology, Xinhua Hospital Affiliated To Shanghai Jiao Tong University School of Medicine, 1665 KongJiang Road, Shanghai, 200092, China.
Rui ZhengDepartment of Pediatric Urology, Xinhua Hospital Affiliated To Shanghai Jiao Tong University School of Medicine, 1665 KongJiang Road, Shanghai, 200092, China.
Zhoutong ChenDepartment of Pediatric Urology, Xinhua Hospital Affiliated To Shanghai Jiao Tong University School of Medicine, 1665 KongJiang Road, Shanghai, 200092, China.
Xia ZhanDepartment of Pediatric Endocrinology and Genetic Metabolism, Shanghai Institute for Pediatric Research, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xiaoliang FangDepartment of Pediatric Urology, Xinhua Hospital Affiliated To Shanghai Jiao Tong University School of Medicine, 1665 KongJiang Road, Shanghai, 200092, China.
Meizhen LiuShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China.
Yongmei LiShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China.
Yonghu XuFudan University Shanghai Cancer Center, Shanghai, China.
Dali LiShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China.
Hongquan GengDepartment of Pediatric Urology, Xinhua Hospital Affiliated To Shanghai Jiao Tong University School of Medicine, 1665 KongJiang Road, Shanghai, 200092, China.
Xiaohui ZhangShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China. zhangxiaohui3040@126.com.
Guofeng XuDepartment of Pediatric Urology, Xinhua Hospital Affiliated To Shanghai Jiao Tong University School of Medicine, 1665 KongJiang Road, Shanghai, 200092, China. xuguofeng@xinhuamed.com.cn.ORCID http://orcid.org/0000-0002-5104-5386
Shanghai Jiao Tong University · CNEast China Normal University · CNFudan University Shanghai Cancer Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cystinuria is a genetic disorder of cystine transport that accounts for 1-2% of all cases of renal lithiasis. It is characterized by hyperexcretion of cystine in urine and recurrent cystine lithiasis. Defective transport of cystine into epithelial cells of renal tubules occurs because of mutations of the transport heterodimer, including protein b

Indexed as

CystinuriaLithiasisAmino Acid Transport Systems, BasicAnimalsCystineFemaleHumansMaleMutationRatsAmino Acid Transport Systems, BasicCystineCRISPR-Cas9 systemCystinuriaRenal cortexSLC7A9Transcriptional profiling

Identifiers

PMID35416493
PMCPMC9110498
OpenAlexW4223501932

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.