Evidence map›Paper›PMID 35416489›Full record

ArticleClinical neuroradiology2022

First-line Double Stentriever Thrombectomy for M1/TICA Occlusions : Initial Experiences.

Pedro Vega, Eduardo Murias, Jose Maria Jimenez, Juan Chaviano, Jose Rodriguez, Sergio Calleja, Montserrat Delgado, Lorena Benavente, Maria Castañon, Josep Puig and 3 more

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Clinical neuroradiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05930145 (A Randomized Study Comparing the Effectiveness and Security of the Use of Two Stentrievers Simultaneously Versus One Stentriever as a Primary Treatment in Acute Ischemic Stroke Patients.), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05930145 narecruitingnot on this mapstarted 2025, after this paper: background citation

A Randomized Study Comparing the Effectiveness and Security of the Use of Two Stentrievers Simultaneously Versus One Stentriever as a Primary Treatment in Acute Ischemic Stroke Patients.

TypeinterventionalSponsorFundación EPICRan2025 to 2026Enrolled200ConditionsStroke, Thrombectomy, Arterial Occlusive DiseasesArmsDouble stentriever, Single stentriever
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Procedural factors associated with successful recanalization in patients with acute ischemic stroke treated with endovascular thrombectomy-a nationwide register-based observational study.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Observational
  3. Article
  4. Benchtop evaluation of a double stent retriever thrombectomy technique for acute ischemic stroke treatment.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Pedro VegaDepartment of Radiology, Hospital Universitario Central de Asturias, Avda. Roma S/N 33011, Oviedo, Asturias, Spain. peveval@yahoo.es.ORCID http://orcid.org/0000-0002-7446-4540
Eduardo MuriasDepartment of Radiology, Hospital Universitario Central de Asturias, Avda. Roma S/N 33011, Oviedo, Asturias, Spain.
Jose Maria JimenezDepartment of Radiology, Hospital Universitario Central de Asturias, Avda. Roma S/N 33011, Oviedo, Asturias, Spain.
Juan ChavianoDepartment of Radiology, Hospital Universitario Central de Asturias, Avda. Roma S/N 33011, Oviedo, Asturias, Spain.
Jose RodriguezDepartment of Radiology, Hospital Universitario Central de Asturias, Avda. Roma S/N 33011, Oviedo, Asturias, Spain.
Sergio CallejaDepartment of Neurology, Hospital Universitario Central de Asturias, Asturias, Spain.
Montserrat DelgadoDepartment of Neurology, Hospital Universitario Central de Asturias, Asturias, Spain.
Lorena BenaventeDepartment of Neurology, Hospital Universitario Central de Asturias, Asturias, Spain.
Maria CastañonDepartment of Neurology, Hospital Universitario Central de Asturias, Asturias, Spain.
Josep PuigIDI-Radiology, Doctor Josep Trueta University Hospital of Girona, Girona, Spain.
Helena CigarranDepartment of Radiology, Hospital Universitario Central de Asturias, Avda. Roma S/N 33011, Oviedo, Asturias, Spain.
Faustino AriasDepartment of Radiology, Hospital Universitario Central de Asturias, Avda. Roma S/N 33011, Oviedo, Asturias, Spain.
Rene ChapotDepartment of Neuroradiology and Intracranial Endovascular Therapy, Alfried Krupp Krankenhaus, Essen, Germany.
Hospital Universitario Central de Asturias · ESAlfried Krupp Hospital · DEHospital Universitari de Girona Doctor Josep Trueta · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMechanical thrombectomy is the standard of care for acute ischemic stroke due to large-vessel occlusion; however, mechanical thrombectomy fails to achieve adequate recanalization in nearly one third of these cases. Rescue therapy using two stentrievers simultaneously yields good results in clots refractory to single stentriever treatment. We aimed to determine the safety and efficacy of first-line double stentriever thrombectomy for acute occlusion of the M1 segment of the middle cerebral artery and/or terminal internal carotid artery (TICA).

methodsThis single-center study prospectively enrolled consecutive patients with a single M1/TICA occlusion to undergo double stentriever thrombectomy between May and October 2020. Outcomes included successful recanalization (modified thrombolysis in cerebral infarction, TICI 2b/3), first-pass effect, procedure times, number of device passes, symptomatic intracerebral hemorrhage, National Institutes of Health Stroke Scale Score (NIHSS) at discharge, 90-day functional independence (modified Rankin scale 0-2), and 90-day mortality.

resultsWe analyzed 39 patients median age 79 years (range 42-96 years); 23 (58.9%) female; 19 (48.7%) with TICA occlusions; 5 (12.8%) with mRS 3-5 at admission; mean NIHSS at admission, 17 ± 4.39). Mean time from symptom onset to final angiogram was 238.0 ± 94.6 min; mean intervention duration was 36.0 ± 24.2 min. The mean number of device passes was 1.5 ± 1.07. All patients had final TICI 2b/3, and 27 (69%) had TICI 2c/3 after the first pass. We observed 3 (7.9%) cases of intracerebral symptomatic hemorrhages. At 90 days, 16 (41%) patients were functionally independent and 9 (23%) had died. The percentage of patients with good clinical outcome at 90 days was 55.5% in the first-pass subgroup.

conclusionOur findings suggest that first-line double stentriever thrombectomy is safe and effective for M1/TICA occlusions.

Indexed as

Brain IschemiaIschemic StrokeStrokeAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective StudiesStentsThrombectomyTreatment OutcomeEndovascular treatmentHemorrhageSingle stentriever rescueStrokeThrombectomy

Identifiers

PMID35416489
PMCPMC9744691
OpenAlexW4223573237

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.