Evidence map›Paper›PMID 35416386›Full record

ArticleAngewandte Chemie (International ed. in English)2022

A Ruthenium(II) Polypyridyl Complex Disrupts Actin Cytoskeleton Assembly and Blocks Cytokinesis.

Martin R Gill, Paul J Jarman, Vanessa Hearnden, Simon D Fairbanks, Marcella Bassetto, Hannes Maib, John Palmer, Kathryn R Ayscough, Jim A Thomas, Carl Smythe

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Exploring the Potential of Metal-Based Candidate Drugs as Modulators of the Cytoskeleton.Chembiochem : a European journal of chemical biology · 2023
    Review
  4. Review
  5. Review
  6. Article
  7. A Ruthenium(II) Polypyridyl Complex Disrupts Actin Cytoskeleton Assembly and Blocks Cytokinesis.Angewandte Chemie (Weinheim an der Bergstrasse, Germany) · 2022
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Martin R GillDepartment of Chemistry, Faculty of Science and Engineering, Swansea University, UK.
Paul J JarmanDepartment of Biomedical Science, University of Sheffield, UK.
Vanessa HearndenDepartment of Materials Science and Engineering, University of Sheffield, UK.
Simon D FairbanksDepartment of Chemistry, University of Sheffield, UK.
Marcella BassettoDepartment of Chemistry, Faculty of Science and Engineering, Swansea University, UK.
Hannes MaibDepartment of Biomedical Science, University of Sheffield, UK.
John PalmerDepartment of Biomedical Science, University of Sheffield, UK.
Kathryn R AyscoughDepartment of Biomedical Science, University of Sheffield, UK.
Jim A ThomasDepartment of Chemistry, University of Sheffield, UK.ORCID 0000-0002-8662-7917
Carl SmytheDepartment of Biomedical Science, University of Sheffield, UK.
University of Sheffield · GBSwansea University · GB

Funding

Biotechnology and Biological Sciences Research Council R/152362Medical Research Council R/162348Wellcome Trust
6 · The paper itself

Abstract

The dinuclear Ru

Indexed as

CytokinesisRutheniumActin CytoskeletonActinsEndosomal Sorting Complexes Required for TransportMolecular Docking SimulationActinsEndosomal Sorting Complexes Required for TransportRutheniumActinCytokinesisCytoskeletonPolypyridyl ComplexesRuthenium

Identifiers

PMID35416386
PMCPMC9323417
OpenAlexW4223437929

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.