Evidence map›Paper›PMID 35416147›Full record

ArticleMicrobial genomics2022

Targeted control of pneumolysin production by a mobile genetic element in

Emily J Stevens, Daniel J Morse, Dora Bonini, Seána Duggan, Tarcisio Brignoli, Mario Recker, John A Lees, Nicholas J Croucher, Stephen Bentley, Daniel J Wilson and 11 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbial genomics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Article
  5. Review
  6. Extensive re-modelling of the cell wall during the development ofbioRxiv : the preprint server for biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 9 institutions in 4 countries.

Emily J StevensSchool of Cellular and Molecular Medicine, University of Bristol, Bristol, BS8 1TD, UK.
Daniel J MorseSchool of Cellular and Molecular Medicine, University of Bristol, Bristol, BS8 1TD, UK.
Dora BoniniSchool of Cellular and Molecular Medicine, University of Bristol, Bristol, BS8 1TD, UK.
Seána DugganSchool of Cellular and Molecular Medicine, University of Bristol, Bristol, BS8 1TD, UK.
Tarcisio BrignoliSchool of Cellular and Molecular Medicine, University of Bristol, Bristol, BS8 1TD, UK.
Mario ReckerCentre for Ecology and Conservation, University of Exeter, Penryn Campus, Exeter, TR10 9FE, UK.
John A LeesMRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, St. Mary's Campus, Imperial College London, London, W2 1PG, UK.
Nicholas J CroucherMRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, St. Mary's Campus, Imperial College London, London, W2 1PG, UK.
Stephen BentleyThe Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.
Daniel J WilsonBig Data Institute, Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK.
Sarah G EarleBig Data Institute, Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK.
Robert DixonBig Data Institute, Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK.
Angela NobbsBristol Dental School, University of Bristol, Bristol, BS1 2LY, UK.
Howard JenkinsonBristol Dental School, University of Bristol, Bristol, BS1 2LY, UK.
Tim van OpijnenBiology Department, Boston College, Chestnut Hill, MA, USA.
Derek ThibaultBiology Department, Boston College, Chestnut Hill, MA, USA.
Oliver J WilkinsonDNA-Protein Interactions Unit, School of Biochemistry, University of Bristol, Bristol, BS8 1TD, UK.
Mark S DillinghamDNA-Protein Interactions Unit, School of Biochemistry, University of Bristol, Bristol, BS8 1TD, UK.
Simon CarlileHost Pathogen Interactions Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland.
Rachel M McLoughlinHost Pathogen Interactions Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland.
Ruth C MasseySchool of Cellular and Molecular Medicine, University of Bristol, Bristol, BS8 1TD, UK.
University of Bristol · GBUniversity of Oxford · GBBoston College · USImperial College London · GBTrinity College Dublin · IEUniversity Of Bristol Dental Hospital · GBUniversity College Cork · IEUniversity of Exeter · GBWellcome Sanger Institute · GB

Funding

Medical Research Council MR/R015600/1Medical Research Council MR/V033417/1Wellcome Trust 101237/Z/13/BWellcome Trust 202846/Z/16/ZWellcome Trust 212258/Z/18/Z
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Genome-Wide Association StudyStreptococcus pneumoniaeAnimalsBacterial ProteinsInterspersed Repetitive SequencesMiceStreptolysinsVirulence FactorsBacterial ProteinsplY protein, Streptococcus pneumoniaeStreptolysinsVirulence FactorsICE elementspneumolysin regulationStreptococcus pneumoniaeZomB protein

Identifiers

PMID35416147
PMCPMC9453066
OpenAlexW4223476272

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.