Evidence map›Paper›PMID 35415802›Full record

ArticleNeurochemical research2022

Nandrolone Supplementation Promotes AMPK Activation and Divergent

N R Strogulski, A Kopczynski, V G de Oliveira, R B Carteri, G Hansel, G T Venturin, S Greggio, J C DaCosta, M A De Bastiani, M S Rodolphi and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Neurochemical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

N R StrogulskiLaboratory of Neurotrauma and Biomarkers, Departamento de Bioquímica, ICBS, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, Brazil.
A KopczynskiLaboratory of Neurotrauma and Biomarkers, Departamento de Bioquímica, ICBS, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, Brazil.
V G de OliveiraLaboratory of Neurotrauma and Biomarkers, Departamento de Bioquímica, ICBS, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, Brazil.
R B CarteriLaboratory of Neurotrauma and Biomarkers, Departamento de Bioquímica, ICBS, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, Brazil.
G HanselNeuroinflammation and Neuroimmunology Laboratory, Brain Institute of Rio Grande Do Sul, Pontifical Catholic University of Rio Grande Do Sul (PUCRS), Porto Alegre, RS, Brazil.
G T VenturinBrain Institute of Rio Grande Do Sul (BraIns), Pontifical Catholic University of Rio Grande Do Sul (PUCRS), Porto Alegre, RS, Brazil.
S GreggioBrain Institute of Rio Grande Do Sul (BraIns), Pontifical Catholic University of Rio Grande Do Sul (PUCRS), Porto Alegre, RS, Brazil.
J C DaCostaBrain Institute of Rio Grande Do Sul (BraIns), Pontifical Catholic University of Rio Grande Do Sul (PUCRS), Porto Alegre, RS, Brazil.
M A De BastianiZimmer Neuroimaging Lab, Departamento de Bioquímica, ICBS, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, Brazil.
M S RodolphiLaboratory of Neurotrauma and Biomarkers, Departamento de Bioquímica, ICBS, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, Brazil.
L V PortelaLaboratory of Neurotrauma and Biomarkers, Departamento de Bioquímica, ICBS, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, Brazil. roskaportela@gmail.com.ORCID http://orcid.org/0000-0001-6113-8466
Universidade Federal do Rio Grande · BRInstituto do Cérebro · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico #4011645/2012-6Conselho Nacional de Desenvolvimento Científico e Tecnológico #5465346/2014-6FAPERGS #1010267FAPERGS/CAPES #19/25510000717-5FAPERGS/PPSUS #17/2551-0001FAPERGS/PRONEX #16/2551-0000499-4
6 · The paper itself

Abstract

Decreased anabolic androgen levels are followed by impaired brain energy support and sensing with loss of neural connectivity during physiological aging, providing a neurobiological basis for hormone supplementation. Here, we investigated whether nandrolone decanoate (ND) administration mediates hypothalamic AMPK activation and glucose metabolism, thus affecting metabolic connectivity in brain areas of adult and aged mice. Metabolic interconnected brain areas of rodents can be detected by positron emission tomography using

Indexed as

Anabolic AgentsNandroloneAMP-Activated Protein KinasesAnimalsBrainDietary SupplementsFluorodeoxyglucose F18GlucoseMiceNandrolone DecanoatePositron-Emission TomographyAMP-Activated Protein KinasesAnabolic AgentsFluorodeoxyglucose F18GlucoseNandroloneNandrolone Decanoate18FDG-PETAgingAnabolic-androgen steroidsMitochondriaNandrolone decanoateNeural metabolic connectivity

Identifiers

PMID35415802
OpenAlexW4223495343

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.