Evidence map›Paper›PMID 35415780›Full record

ArticleInternational journal of computer assisted radiology and surgery2022

Pseudo low-energy monochromatic imaging of head and neck cancers: Deep learning image reconstruction with dual-energy CT.

Yuhei Koike, Shingo Ohira, Yuri Teraoka, Ayako Matsumi, Yasuhiro Imai, Yuichi Akino, Masayoshi Miyazaki, Satoaki Nakamura, Koji Konishi, Noboru Tanigawa and 1 more

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Article in International journal of computer assisted radiology and surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Systematic Review on Learning-based Spectral CT.IEEE transactions on radiation and plasma medical sciences · 2024
    Article
  7. Article
  8. Review
  9. Acquisition time reduction in pediatricJournal of applied clinical medical physics · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yuhei KoikeDepartment of Radiology, Kansai Medical University, 2-5-1 Shinmachi, Hirakata, Osaka, 573-1010, Japan. koikeyuh@hirakata.kmu.ac.jp.ORCID http://orcid.org/0000-0003-3963-4257
Shingo OhiraDepartment of Radiation Oncology, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka, 537-8567, Japan.
Yuri TeraokaGE Healthcare Japan Corporation, 4-7-127 Asahigaoka, Hino, Tokyo, 191-8503, Japan.
Ayako MatsumiGE Healthcare Japan Corporation, 4-7-127 Asahigaoka, Hino, Tokyo, 191-8503, Japan.
Yasuhiro ImaiGE Healthcare Japan Corporation, 4-7-127 Asahigaoka, Hino, Tokyo, 191-8503, Japan.
Yuichi AkinoDepartment of Radiation Oncology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Masayoshi MiyazakiDepartment of Radiation Oncology, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka, 537-8567, Japan.
Satoaki NakamuraDepartment of Radiology, Kansai Medical University, 2-5-1 Shinmachi, Hirakata, Osaka, 573-1010, Japan.
Koji KonishiDepartment of Radiation Oncology, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka, 537-8567, Japan.
Noboru TanigawaDepartment of Radiology, Kansai Medical University, 2-5-1 Shinmachi, Hirakata, Osaka, 573-1010, Japan.
Kazuhiko OgawaDepartment of Radiation Oncology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.

Funding

Japan Society for the Promotion of Science 20K16742Japan Society for the Promotion of Science 21K07742
6 · The paper itself

Abstract

purposeLow-energy virtual monochromatic images (VMIs) derived from dual-energy computed tomography (DECT) systems improve lesion conspicuity of head and neck cancer over single-energy CT (SECT). However, DECT systems are installed in a limited number of facilities; thus, only a few facilities benefit from VMIs. In this work, we present a deep learning (DL) architecture suitable for generating pseudo low-energy VMIs of head and neck cancers for facilities that employ SECT imaging.

methodsWe retrospectively analyzed 115 patients with head and neck cancers who underwent contrast enhanced DECT. VMIs at 70 and 50 keV were used as the input and ground truth (GT), respectively. We divided them into two datasets: for DL (104 patients) and for inference with SECT (11 patients). We compared four DL architectures: U-Net, DenseNet-based, and two ResNet-based models. Pseudo VMIs at 50 keV (pVMI

resultsU-Net produced the lowest MAE (13.32 ± 2.20 HU) and highest PSNR (47.03 ± 2.33 dB) and SSIM (0.9965 ± 0.0009), with statistically significant differences (P < 0.001). The HU evaluation showed good agreement between the GT and U-Net. U-Net produced the smallest absolute HU difference for the tumor, at < 5.0 HU.

conclusionQuantitative comparisons of physical parameters demonstrated that the proposed U-Net could generate high accuracy pVMI

Indexed as

Deep LearningHead and Neck NeoplasmsRadiography, Dual-Energy Scanned ProjectionHumansImage Processing, Computer-AssistedRetrospective StudiesTomography, X-Ray ComputedDeep learningDual-energy CTHead and neckVirtual monochromatic image

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.