Evidence map›Paper›PMID 35415688›Full record

ArticleFood chemistry. Molecular sciences2022

Dietary fatty acid metabolism: New insights into the similarities of lipid metabolism in humans and hamsters.

Alaitz Berriozabalgoitia, Juan Carlos Ruiz de Gordoa, Gustavo Amores, Mailo Virto

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Food chemistry. Molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. CS27109, A Selective Thyroid Hormone Receptor-International journal of endocrinology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alaitz BerriozabalgoitiaLactiker Research Group, Department of Biochemistry and Molecular Biology, University of the Basque Country UPV/EHU, Paseo de la Universidad 7, 01006 Vitoria-Gasteiz, Spain.
Juan Carlos Ruiz de GordoaLactiker Research Group, Department of Biochemistry and Molecular Biology, University of the Basque Country UPV/EHU, Paseo de la Universidad 7, 01006 Vitoria-Gasteiz, Spain.
Gustavo AmoresLactiker Research Group, Department of Biochemistry and Molecular Biology, University of the Basque Country UPV/EHU, Paseo de la Universidad 7, 01006 Vitoria-Gasteiz, Spain.
Mailo VirtoLactiker Research Group, Department of Biochemistry and Molecular Biology, University of the Basque Country UPV/EHU, Paseo de la Universidad 7, 01006 Vitoria-Gasteiz, Spain.
University of the Basque Country · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hamsters have been long accepted as animal models to study the lipid metabolism in humans. However, very few scientific works described in detail the fatty acid (FA) composition of plasma and erythrocytes in hamsters in relation to their dietary intake, and none work was found comparing them with that described in humans. Therefore, a study was carried out to compare the effect of ingesting olive oil or dairy fat, as part of an equilibrated diet in healthy subjects, on plasma and erythrocytes FA composition. More than 40 FA were detected in samples of both species. It was demonstrated that plasma total FA (TFA) concentration and FA profiles are similar in humans and hamsters. In both species linoleic, oleic and palmitic acids are the main FA and accounted for the 70% of TFA. Differences found between species can be explained by differences in the dietary intake and differences in the proportion of triglycerides, cholesteryl esters and phospholipid fractions in plasma of both species. Changes in dietary FA intake causes similar changes in FA concentration in the plasma of both species and can be explained by the same metabolic processes. The erythrocyte FA profile differs more between the two species. Moreover, unlike humans, the FA profile of hamster erythrocytes is more sensitive to changes in dietary FA than that of plasma.

Indexed as

ALA, Alpha-linolenic acidAnimal modelsARA, Arachidonic acidBCFA, Methyl-branched chain fatty acidsCE, Cholesteryl estersCLA, Conjugated linoleic acidsc-MUFA, cis-Monounsaturated fatty acidsD6D, Delta-6 desaturaseDairy fatDHA, Docosahexaenoic acidEPA, Eicosapentaenoic acidErythrocytesFAME, Fatty acid methyl estersFatty acidsFatty acids/metabolismHamstersLA, Linoleic acidLCPUFA, Long chain polyunsaturated fatty acidsLCSFA, Long chain saturated fatty acidsMCSFA, Medium-chain saturated fatty acidsOA, Oleic acidOlive oilPlasmaPL, PhospholipdsPUFA, Polyunsaturated fatty acidsRA, Rumenic acidSCD-1, Stearoyl-CoA desaturase-1SFA, Saturated fatty acidsTC, Total CholesterolTFA, Total fatty acidsTG, Triglyceridest-MUFA, trans-Monounsaturated fatty acidsVA, Vaccenic acid

Identifiers

PMID35415688
PMCPMC8991696
OpenAlexW4200227405

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.