The effects of the phytochemistry of cocoa on the food chemistry of chocolate(s) and how disease resistance in cocoa can be improved using CRISPR/Cas9 technology.

Peter Mudiaga Etaware

Open access · goldAbstract readReview

In one paragraph

Review in Food chemistry. Molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it

0cells of the map it votes in

3citing papers in PubMed

2.9field-weighted citation impact, top 11% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

CRISPR-Cas technology secures sustainability through its applications: a review in green biotechnology.3 Biotech · 2023
Review
Critical evaluation of the agro-ecological system of the Republic of South Africa (30°S) in response to unclassified claims of cocoa farming beyond 20°S of the equator.PloS one · 2023
Review
Determinants of Cocoa Farmers' Compliance with Agrochemical Safety Precautions in Ogun and Osun States, Nigeria.Toxics · 2022
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Peter Mudiaga EtawareDepartment of Botany, Faculty of Science, University of Ibadan, Ibadan, Oyo State, Nigeria.

University of Ibadan · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Consumers' rating of "chocolate brands" are majorly based on texture and taste rather than packaging. The texture/taste of a chocolate bar is largely influenced by the cocoa variety used for its production, whereas, its bioactive constituent is directly affected by the seed processing/chocolate manufacturing technique(s) adopted, and the additives used. Cacao is the key ingredient for chocolate production; therefore, the choicest varieties must be used to protect consumers' interest. Currently, the availability of the African variety is the only reason why it is globally sought-after for chocolate production rather than its taste. Therefore, a transfer of genetic materials from quality cocoa breeds into the high-yielding and resilient African variety or vice versa, would inferably increase the availability of quality cocoa beans all-year-round, and also increase the chances of obtaining sumptuous and palatable chocolates anywhere in the world.

Indexed as

AFLP, Amplification Fragment Length PolymorphismAnthocyanin (PubChem CID: 11979368)BbsI, Biobricks Standard Idempotency (Restriction Endonuclease)Cacao beansCaffeine (PubChem CID: 2519)Cas9, CRISPR-associated protein 9(-)-Catechin (PubChem CID: 73160)cGMP, Cyclic Guanosine MonophosphateChocolateCRISPR/Cas9 technology for gene editingCRISPR, Clustered Regularly Interspaced Short Palindromic RepeatscrRNA, CRISPR RNACTAB, Cetyl trimethylammonium bromidedCAPs, Derived Cleaved Amplified Polymorphic SequencesDisease resistanceEcoRI, Restriction Endonuclease Enzyme isolated from E. colieNOS, Endothelium-derived Nitric Oxide SynthaseEpicatechin (PubChem CID: 1203)Food chemistryGenetically modified hybridsHDL, High-Density LipoproteinHindIII, Site-specific Deoxyribonuclease Enzyme from Haemophilus InfluenzaeIL-1 to IL-10, Interleukin 1 to 10LDL, Low-Density LipoproteinOleic acid (PubChem CID: 445639)ORAC, Oxygen Radical Absorbance CapacityPalmitic acid (PubChem CID: 9881577)PAM, Protospacer-Adjacent MotifPCR, Polymerase Chain ReactionPhytochemicalsProanthocyanidin (PubChem CID: 108065)psgR-Cas9-At, Phosphorylated Single Guide RNA-Cas9-AtRDA, Recommended Dietary AllowanceRFLP, Restriction Fragment Length PolymorphismROS, Reactive Oxygen SpeciessgRNA, Single Guide Ribonucleic AcidStearic acid (PubChem CID: 5281)T-DNA, Transfer Deoxyribonucleic AcidT generation, Transgenic generationTheobromine (PubChem CID: 5429)Theophylline (PubChem CID: 2153)TNF-a, Tumor Necrosis Factor “a”tracrRNA, Trans-Activating CRISPR RNA

Identifiers

PMID35415660

DOI10.1016/j.fochms.2021.100043

PMCPMC8991945

OpenAlexW3202509983

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.