Evidence map›Paper›PMID 35415299›Full record

ReviewBioactive materials2022

Flexible polymeric patch based nanotherapeutics against non-cancer therapy.

Houjuan Zhu, Justin Mah Jian Qiang, Chen Gang Wang, Chui Yu Chan, Qiang Zhu, Enyi Ye, Zibiao Li, Xian Jun Loh

Open access · goldAbstract readReview
In one paragraph

Review in Bioactive materials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Microneedles forMaterials today. Bio · 2023
    Review
  13. Review
  14. Therapeutic application of hydrogels for bone-related diseases.Frontiers in bioengineering and biotechnology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Houjuan ZhuInstitute of Materials Research and Engineering, ASTAR (Agency for Science, Technology and Research), Singapore, 138634, Singapore.
Justin Mah Jian QiangInstitute of Materials Research and Engineering, ASTAR (Agency for Science, Technology and Research), Singapore, 138634, Singapore.
Chen Gang WangInstitute of Materials Research and Engineering, ASTAR (Agency for Science, Technology and Research), Singapore, 138634, Singapore.
Chui Yu ChanInstitute of Materials Research and Engineering, ASTAR (Agency for Science, Technology and Research), Singapore, 138634, Singapore.
Qiang ZhuInstitute of Materials Research and Engineering, ASTAR (Agency for Science, Technology and Research), Singapore, 138634, Singapore.
Enyi YeInstitute of Materials Research and Engineering, ASTAR (Agency for Science, Technology and Research), Singapore, 138634, Singapore.
Zibiao LiInstitute of Materials Research and Engineering, ASTAR (Agency for Science, Technology and Research), Singapore, 138634, Singapore.
Xian Jun LohInstitute of Materials Research and Engineering, ASTAR (Agency for Science, Technology and Research), Singapore, 138634, Singapore.
Agency for Science, Technology and Research · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Flexible polymeric patches find widespread applications in biomedicine because of their biological and tunable features including excellent patient compliance, superior biocompatibility and biodegradation, as well as high loading capability and permeability of drug. Such polymeric patches are classified into microneedles (MNs), hydrogel, microcapsule, microsphere and fiber depending on the formed morphology. The combination of nanomaterials with polymeric patches allows for improved advantages of increased curative efficacy and lowered systemic toxicity, promoting on-demand and regulated drug administration, thus providing the great potential to their clinic translation. In this review, the category of flexible polymeric patches that are utilized to integrate with nanomaterials is briefly presented and their advantages in bioapplications are further discussed. The applications of nanomaterials embedded polymeric patches in non-cancerous diseases were also systematically reviewed, including diabetes therapy, wound healing, dermatological disease therapy, bone regeneration, cardiac repair, hair repair, obesity therapy and some immune disease therapy. Alternatively, the limitations, latest challenges and future perspectives of such biomedical therapeutic devices are addressed.

Indexed as

Biomedical scaffoldsFlexible polymeric patchesHydrogelMicroneedleNanomaterialsNon-cancer therapy

Identifiers

PMID35415299
PMCPMC8971585
OpenAlexW4221056960

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.