Evidence map›Paper›PMID 35415278›Full record

ArticleSynthetic and systems biotechnology2022

Toehold switch based biosensors for sensing the highly trafficked rosewood

Paul Soudier, Daniel Rodriguez Pinzon, Tristan Reif-Trauttmansdorff, Hassan Hijazi, Maëva Cherrière, Cátia Goncalves Pereira, Doriane Blaise, Maxime Pispisa, Angelyne Saint-Julien, William Hamlet and 6 more

Abstract read
In one paragraph

Article in Synthetic and systems biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Paul SoudierEvry Paris-Saclay 2020 iGEM team, France.
Daniel Rodriguez PinzonEvry Paris-Saclay 2020 iGEM team, France.
Tristan Reif-TrauttmansdorffEvry Paris-Saclay 2020 iGEM team, France.
Hassan HijaziEvry Paris-Saclay 2020 iGEM team, France.
Maëva CherrièreEvry Paris-Saclay 2020 iGEM team, France.
Cátia Goncalves PereiraEvry Paris-Saclay 2020 iGEM team, France.
Doriane BlaiseEvry Paris-Saclay 2020 iGEM team, France.
Maxime PispisaEvry Paris-Saclay 2020 iGEM team, France.
Angelyne Saint-JulienEvry Paris-Saclay 2020 iGEM team, France.
William HamletEvry Paris-Saclay 2020 iGEM team, France.
Melissa NguevoEvry Paris-Saclay 2020 iGEM team, France.
Eva GomesEvry Paris-Saclay 2020 iGEM team, France.
Sophia BelkhelfaEvry Paris-Saclay 2020 iGEM team, France.
Anna NiarakisEvry Paris-Saclay 2020 iGEM team, France.
Manish KushwahaEvry Paris-Saclay 2020 iGEM team, France.
Ioana GrigorasEvry Paris-Saclay 2020 iGEM team, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nucleic acid sensing is a 3 decades old but still challenging area of application for different biological sub-domains, from pathogen detection to single cell transcriptomics analysis. The many applications of nucleic acid detection and identification are mostly carried out by PCR techniques, sequencing, and their derivatives used at large scale. However, these methods' limitations on speed, cost, complexity and specificity have motivated the development of innovative detection methods among which nucleic acid biosensing technologies seem promising. Toehold switches are a particular class of RNA sensing devices relying on a conformational switch of secondary structure induced by the pairing of the detected trigger RNA with a

Indexed as

BiosensorCITES, Convention on International Trade in Endangered Species of Wild Fauna and FloreCUHK, Chinese University of Hong KongMatK, Maturase KMEFL, Molecules of Equivalent FluoresceinMFE, Minimum free energyRbcL, Ribulose bisphosphate carboxylase large chainRBS, Ribosome binding siteRiboregulatorRosewoodToehold switchTrnL-UAA, Transfer RNA Leucine UAA

Identifiers

PMID35415278
PMCPMC8976095

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.