Evidence map›Paper›PMID 35415201›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)2022

A highly feasible, reliable, and fully remote protocol for mobile app-based cognitive assessment in cognitively healthy older adults.

Louisa I Thompson, Karra D Harrington, Nelson Roque, Jennifer Strenger, Stephen Correia, Richard N Jones, Stephen Salloway, Martin J Sliwinski

Abstract read
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed.

  1. Article
  2. Technology-natives and technology-adopters: Age differences in remote cognitive assessment in Alzheimer disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  3. Visual Working Memory in Older Adults With and Without Early-Onset Depression: An Ecological Momentary Assessment Study.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2026
    Article
  4. Article
  5. Article
  6. Not just how much, but how it's done: movement activity bout distributions and everyday cognition in older adults with elevated dementia risk.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Computational Phenotyping of Cognitive Decline With Retest Learning.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Louisa I ThompsonDepartment of Psychiatry and Human Behavior Alpert Medical School Brown University Providence Rhode Island USA.
Karra D HarringtonCenter for Healthy Aging Penn State University University Park Pennsylvania USA.
Nelson RoqueDepartment of Psychology University of Central Florida Orlando Florida USA.
Jennifer StrengerDepartment of Psychiatry and Human Behavior Alpert Medical School Brown University Providence Rhode Island USA.
Stephen CorreiaDepartment of Psychiatry and Human Behavior Alpert Medical School Brown University Providence Rhode Island USA.
Richard N JonesDepartment of Psychiatry and Human Behavior Alpert Medical School Brown University Providence Rhode Island USA.
Stephen SallowayDepartment of Psychiatry and Human Behavior Alpert Medical School Brown University Providence Rhode Island USA.
Martin J SliwinskiCenter for Healthy Aging Penn State University University Park Pennsylvania USA.

Funding

Ambulatory Methods for Measuring Cognitive ChangeU2CAG060408 · NIA · PENNSYLVANIA STATE UNIVERSITY, THE · PI CHINCHILLI, VERNON M · 2018 to 2022
$14.9M
Psychosocial Determinants and Biological Pathway to Healthy Aging (Pathways)T32AG049676 · NIA · PENNSYLVANIA STATE UNIVERSITY, THE · PI LYNN M. MARTIRE · 2016 to 2026
$3.9M
NIA NIH HHS L30 AG074462NIA NIH HHS T32 AG049676NIA NIH HHS U2C AG060408
6 · The paper itself

Abstract

Introduction: The early detection of cognitive impairment is one of the most important challenges in Alzheimer's disease (AD) research. The use of brief, short-term repeated test sessions via mobile app has demonstrated similar or better reliability and validity compared to standard in-clinic assessments in adult samples. The present study examined adherence, acceptability, and reliability for a remote, app-based cognitive screening protocol in healthy older adults. Methods: Cognitively unimpaired older adults ( Results: Participants completed an average of 93% (M = 22.3 sessions, standard deviation = 10.2) of the 24 assigned sessions within 8 to 9 days. Average daily adherence ranged from 95% of sessions completed on day 2 to 88% of sessions completed on day 8. There was a statistically significant effect of session time on adherence between the morning and afternoon sessions only Discussion: These findings suggests that remote, mobile app-based cognitive testing in short bursts is both highly feasible and reliable in a motivated sample of cognitively normal older adults. Limitations include the limited diversity and generalizability of the sample; this was a largely White, highly educated, and motivated sample self-selected for AD research.

Indexed as

Cognitive testingdigital testsearly detectionmemorymonitoringpre‐clinical Alzheimer's diseaseremote assessmentscreeningsmartphone app

Identifiers

PMID35415201
PMCPMC8984238

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.