Evidence map›Paper›PMID 35415037›Full record

ArticleCureus2022

SARS-CoV-2 Vaccination Coverage and Key Public Health Indicators May Explain Disparities in COVID-19 Country-Specific Case Fatality Rate Within European Economic Area.

Vasileios P Papadopoulos, Anatoli Emmanouilidou, Marios Yerou, Stefanos Panagaris, Chousein Souleiman, Despoina Varela, Peny Avramidou, Evangelia Melissopoulou, Chrysostomos Pappas, Zoi Iliadou and 6 more

Abstract read
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Vasileios P PapadopoulosDepartment of Internal Medicine, General Hospital of Xanthi, Xanthi, GRC.
Anatoli EmmanouilidouDepartment of Internal Medicine, General Hospital of Xanthi, Xanthi, GRC.
Marios YerouDepartment of Internal Medicine, General Hospital of Xanthi, Xanthi, GRC.
Stefanos PanagarisDepartment of Internal Medicine, General Hospital of Xanthi, Xanthi, GRC.
Chousein SouleimanDepartment of Internal Medicine, General Hospital of Xanthi, Xanthi, GRC.
Despoina VarelaDepartment of Internal Medicine, General Hospital of Xanthi, Xanthi, GRC.
Peny AvramidouDepartment of Internal Medicine, General Hospital of Xanthi, Xanthi, GRC.
Evangelia MelissopoulouDepartment of Internal Medicine, General Hospital of Xanthi, Xanthi, GRC.
Chrysostomos PappasDepartment of Internal Medicine, General Hospital of Xanthi, Xanthi, GRC.
Zoi IliadouDepartment of Internal Medicine, General Hospital of Xanthi, Xanthi, GRC.
Ilias PiperopoulosDepartment of Internal Medicine, General Hospital of Xanthi, Xanthi, GRC.
Vasileios SomadisDepartment of Internal Medicine, General Hospital of Xanthi, Xanthi, GRC.
Anestis PartsalidisDepartment of Internal Medicine, General Hospital of Xanthi, Xanthi, GRC.
Eleni MetaxaDepartment of Internal Medicine, General Hospital of Xanthi, Xanthi, GRC.
Ioannis FeresiadisDepartment of Internal Medicine, General Hospital of Xanthi, Xanthi, GRC.
Dimitrios FilippouSurgery, National and Kapodistrian University of Athens, Athens, GRC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim To investigate the reasons for disparity regarding the country-specific COVID-19-related case fatality rate (CFR) within the 30 countries of the European Economic Area (EEA). Materials and methods Data regarding population, area, COVID-19-associated infections/deaths, vaccination, life expectancy, elderly population, infant mortality, gender disparity, urbanization, gross domestic product (GDP), income per capita, health spending per capita, physicians, nursing personnel, hospital beds, ICU beds, hypertension, diabetes, obesity, and smoking from all EEA countries were collected from official sources on January 16, 2022. Correlation coefficients were computed, and optimal scaling using ridge regression was used to reach the most parsimonious multivariate model assessing any potential independent correlation of public health parameters with COVID-19 CFR. Results COVID-19 CFR ranges from 0.1% (Iceland) to 4.0% (Bulgaria). All parameters but population density, GDP, total health spending (% of GDP), ICU beds, diabetes, and obesity were correlated with COVID-19 CFR. In the most parsimonious multivariate model, elderly population rate (P = 0.018), males/total ratio (P = 0.013), nurses/hospital beds (P = 0.001), physicians/hospital beds (P = 0.026), public health spending (P = 0.013), smoking rate (P = 0.013), and unvaccinated population rate (P = 0.00005) were demonstrated to present independent correlation with COVID-19 CFR. In detail, the COVID-19 CFR is estimated to increase by 1.24 times in countries with vaccination rate of <0.34, 1.11 times in countries with an elderly population rate of ≥0.20, 1.14 times in countries with male ratio values ≥0.493, 1.12 times in countries spending <2,000$ annually per capita for public health, 1.14 and 1.10 times in countries with <2.30 nurses and <0.88 physicians per hospital bed, respectively, and 1.12 in countries with smoking ratio ≥0.22, while holding all other independent variables of the model constant. Conclusion COVID-19 CFR varies substantially among EEA countries and is independently linked with low vaccination rates, increased elderly population rate, diminished public health spending per capita, insufficient physicians and nursing personnel per hospital bed, and prevalent smoking habits. Therefore, public health authorities are awaited to consider these parameters in prioritizing actions to manage the SARS-CoV-2 pandemic.

Indexed as

case fatality ratecovid-19european economic areahealth spendingsmokingvaccination

Identifiers

PMID35415037
PMCPMC8994019

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.