ArticleBiomedical optics express2022
Evaluation of resonant scanning as a high-speed imaging technique for two-photon imaging of cortical vasculature.
Article in Biomedical optics express, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Persistent dysmorphology and dysfunction of the brain microvasculature following repeated trauma.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026Article
- Review
- Improving vascular retention of indocyanine green forJournal of biomedical optics · 2025Article
- Non-degenerate two-photon imaging of deep rodent cortex using indocyanine green in the water absorption window.Biomedical optics express · 2024Article
- Suppression of Subpixel Jitter in Resonant Scanning Systems With Phase-locked Sampling.IEEE transactions on medical imaging · 2024Article
- A Deep Learning Approach for Improving Two-Photon Vascular Imaging Speeds.Bioengineering (Basel, Switzerland) · 2024Article
- Non-Degenerate Two-Photon Imaging of Deep Rodent Cortex using Indocyanine Green in the water absorption window.bioRxiv : the preprint server for biology · 2024Article
- Avoiding bias in fluorescence sensor readout.Nature reviews. Neuroscience · 2024Article
- Pulse train gating to improve signal generation forNeurophotonics · 2023Article
- Design and test of a rigid endomicroscopic system for multimodal imaging and femtosecond laser ablation.Journal of biomedical optics · 2023Article
- Pulse train gating to improve signal generation forbioRxiv : the preprint server for biology · 2023Article
- Deep learning-based high-speed, large-field, and high-resolution multiphoton imaging.Biomedical optics express · 2023Article
- Diamond Raman laser and Yb fiber amplifier forBiomedical optics express · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
We demonstrate a simple, low-cost two-photon microscope design with both galvo-galvo and resonant-galvo scanning capabilities. We quantify and compare the signal-to-noise ratios and imaging speeds of the galvo-galvo and resonant-galvo scanning modes when used for murine neurovascular imaging. The two scanning modes perform as expected under shot-noise limited detection and are found to achieve comparable signal-to-noise ratios. Resonant-galvo scanning is capable of reaching desired signal-to-noise ratios using less acquisition time when higher excitation power can be used. Given equal excitation power and total pixel dwell time between the two methods, galvo-galvo scanning outperforms resonant-galvo scanning in image quality when detection deviates from being shot-noise limited.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.