ArticleBiomedical optics express2022
Complete head cerebral sensitivity mapping for diffuse correlation spectroscopy using subject-specific magnetic resonance imaging models.
Article in Biomedical optics express, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 35 citations in OpenAlex.
- Monte Carlo simulations of time-resolved blood flow index: times-of-flight beyond ∼1 ns are necessary for brain-dominated measurements.Neurophotonics · 2026Article
- CoMind R1: a time-resolved interferometric optical neuromonitoring system for pulsatile cerebral blood flow measurement at late times-of-flight.Neurophotonics · 2026Article
- Comparative validation of speckle contrast optical spectroscopy against diffuse correlation spectroscopy for monitoring human cerebral blood flow.Neurophotonics · 2026Article
- Correlation between diffuse correlation spectroscopy and transcranial Doppler ultrasound in pediatric sickle cell disease.Biomedical optics express · 2026Article
- Comparison of diffuse correlation spectroscopy analytical models for cerebral blood flow measurements.Journal of biomedical optics · 2025Article
- Light transport in the human spine for optical bone density assessment: Monte Carlo modeling and validation.Biomedical optics express · 2025Article
- Cerebral blood flow monitoring using a deep learning implementation of the two-layer diffuse correlation spectroscopy analytical model with a 512 × 512 SPAD array.Neurophotonics · 2025Article
- Beneath the surface: revealing deep-tissue blood flow in human subjects with massively parallelized diffuse correlation spectroscopy.Neurophotonics · 2025Article
- A compact time-domain diffuse optical tomography system for cortical neuroimaging.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Revisiting equivalent optical properties for cerebrospinal fluid to improve diffusion-based modeling accuracy in the brain.Neurophotonics · 2025Article
- Revisiting equivalent optical properties for cerebrospinal fluid to improve diffusion-based modeling accuracy in the brain.bioRxiv : the preprint server for biology · 2024Article
- How the heterogeneity of the severely injured brain affects hybrid diffuse optical signals: case examples and guidelines.Neurophotonics · 2024Article
- All-optics technique for monitoring absolute cerebral blood flow: validation against magnetic resonance imaging perfusion.Neurophotonics · 2024Article
- Modified Beer-Lambert algorithm to measure pulsatile blood flow, critical closing pressure, and intracranial hypertension.Biomedical optics express · 2024Article
- Time-domain diffuse correlation spectroscopy at large source detector separation for cerebral blood flow recovery.Biomedical optics express · 2024Article
- Assessing changes in regional cerebral hemodynamics in adults with a high-density full-head coverage time-resolved near-infrared spectroscopy device.Journal of biomedical optics · 2024Article
- Introduction to the Optics and the Brain 2023 feature issue.Biomedical optics express · 2024Article
- Validation of the Openwater wearable optical system: cerebral hemodynamic monitoring during a breath-hold maneuver.Neurophotonics · 2024Article
- Article
- Comparison of diffuse correlation spectroscopy analytical models for measuring cerebral blood flow in adults.Journal of biomedical optics · 2023Article
Corrections and comments
- Erratum issued
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
We characterize cerebral sensitivity across the entire adult human head for diffuse correlation spectroscopy, an optical technique increasingly used for bedside cerebral perfusion monitoring. Sixteen subject-specific magnetic resonance imaging-derived head models were used to identify high sensitivity regions by running Monte Carlo light propagation simulations at over eight hundred uniformly distributed locations on the head. Significant spatial variations in cerebral sensitivity, consistent across subjects, were found. We also identified correlates of such differences suitable for real-time assessment. These variations can be largely attributed to changes in extracerebral thickness and should be taken into account to optimize probe placement in experimental settings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.