ArticleQuantitative biology (Beijing, China)2021
Integrative modeling of transmitted and
Article in Quantitative biology (Beijing, China), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Statistical methods for assessing the effects of de novo variants on birth defects.Human genomics · 2024Review
- Network assisted analysis of de novo variants using protein-protein interaction information identified 46 candidate genes for congenital heart disease.PLoS genetics · 2022Article
- Computational Genomics in the Era of Precision Medicine: Applications to Variant Analysis and Gene Therapy.Journal of personalized medicine · 2022Review
- M-DATA: A statistical approach to jointly analyzing de novo mutations for multiple traits.PLoS genetics · 2021Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Background: Whole-exome sequencing (WES) studies have identified multiple genes enriched for Methods: In this manuscript, we introduce a hierarchical Bayesian framework for gene-level association test which jointly analyzes Results: Applied to WES data of 2,645 CHD proband-parent trios, our method identified 15 significant genes, half of which are novel, leading to new insights into the genetic bases of CHD. Conclusion: These results showcase the power of integrative analysis of transmitted and
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.