Evidence map›Paper›PMID 35414887›Full record

ArticleChemical science2022

Phosphine-catalyzed divergent domino processes between γ-substituted allenoates and carbonyl-activated alkenes.

Mingyue Wu, Zhaobin Han, Huanzhen Ni, Nengzhong Wang, Kuiling Ding, Yixin Lu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mingyue WuDepartment of Chemistry, National University of Singapore 3 Science Drive 3 Singapore 117543 Singapore chmlyx@nus.edu.sg.
Zhaobin HanState Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences 345 Lingling Road Shanghai 200032 China kding@mail.sioc.ac.cn.
Huanzhen NiDepartment of Chemistry, National University of Singapore 3 Science Drive 3 Singapore 117543 Singapore chmlyx@nus.edu.sg.
Nengzhong WangDepartment of Chemistry, National University of Singapore 3 Science Drive 3 Singapore 117543 Singapore chmlyx@nus.edu.sg.
Kuiling DingState Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences 345 Lingling Road Shanghai 200032 China kding@mail.sioc.ac.cn.
Yixin LuDepartment of Chemistry, National University of Singapore 3 Science Drive 3 Singapore 117543 Singapore chmlyx@nus.edu.sg.ORCID https://orcid.org/0000-0002-5730-166X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Highly enantioselective and chemodivergent domino reactions between γ-substituted allenoates and activated alkenes have been developed. In the presence of NUSIOC-Phos, triketone enone substrates smoothly reacted with γ-substituted allenoates to form bicyclic furofurans in good yields with high stereoselectivities. Alternatively, the reaction between diester-activated enone substrates and γ-substituted allenoates formed chiral conjugated 1,3-dienes in good yields with excellent enantioselectivities. Notably, by employing substrates with subtle structural difference, under virtually identical reaction conditions, we were able to access two types of chiral products, which are of biological relevance and synthetic importance.

Identifiers

PMID35414887
PMCPMC8926293

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.