Evidence map›Paper›PMID 35414856›Full record

ReviewMethodist DeBakey cardiovascular journal2022

Clinical Clues and Diagnostic Workup of Cardiac Amyloidosis.

Sajan S Gill, Eric Fellin, Lisa Stampke, Yunazi Zhao, Ahmad Masri

Open access · diamondAbstract readReview
In one paragraph

Review in Methodist DeBakey cardiovascular journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sajan S GillKnight Cardiovascular Institute, Oregon Health & Science University School of Medicine, Portland, Oregon, US.ORCID https://orcid.org/0000-0002-9156-7103
Eric FellinOregon Health & Science University School of Medicine, Portland, Oregon, US.
Lisa StampkeOregon Health & Science University School of Medicine, Portland, Oregon, US.
Yunazi ZhaoKnight Cardiovascular Institute, Oregon Health & Science University School of Medicine, Portland, Oregon, US.
Ahmad MasriKnight Cardiovascular Institute, Oregon Health & Science University School of Medicine, Portland, Oregon, US.ORCID https://orcid.org/0000-0002-6390-6526
Oregon Health & Science University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac amyloidosis is increasingly recognized as an underlying cause of left ventricular wall thickening, heart failure, and arrhythmia with variable clinical presentation. Due to the subtle cardiac findings in early transthyretin cardiac amyloidosis and the availability of therapies that can modify but not reverse the disease progression, early recognition is vital. In light chain amyloidosis, timely diagnosis and treatment can significantly improve survival. In this manuscript, we review the clinical, imaging, and electrocardiographic clues that should raise suspicion for cardiac amyloidosis and provide a simplified diagnostic workup algorithm that ensures an accurate diagnosis. The evolution of the noninvasive diagnosis of cardiac amyloidosis has significantly influenced our understanding of disease prevalence, presentations, and outcomes. However, clinical recognition of clues and red flags remains the most important factor in advancing the care of patients with cardiac amyloidosis.

Indexed as

Amyloid Neuropathies, FamilialCardiomyopathiesHumansaortic stenosisbone scintigraphycardiac amyloidosiscardiac magnetic resonance imagingendomyocardial biopsyheart failureimmunoglobulin light chainleft ventricular hypertrophysystemic amyloidosistransthyretin

Identifiers

PMID35414856
PMCPMC8932349
OpenAlexW4225584694

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.