Evidence map›Paper›PMID 35414772›Full record

ReviewInternational journal of biological sciences2022

Immunologic Memory in Pregnancy: Focusing on Memory Regulatory T Cells.

Yu-Jing Zhang, Li Shen, Tao Zhang, Kahindo P Muyayalo, Jing Luo, Gil Mor, Ai-Hua Liao

Open access · goldAbstract readReview
In one paragraph

Review in International journal of biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Regulatory T-Cells During Pregnancy Relate to Women's Own Childhood History of Microbial Exposure.American journal of human biology : the official journal of the Human Biology Council · 2025
    Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Yu-Jing ZhangInstitute of Reproductive Health, Center for Reproductive Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China.
Li ShenDepartment of Obstetrics and Gynecology, Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China.
Tao ZhangDepartment of Obstetrics and Gynaecology, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, P.R. China.
Kahindo P MuyayaloInstitute of Reproductive Health, Center for Reproductive Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China.
Jing LuoInstitute of Reproductive Health, Center for Reproductive Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China.
Gil MorInstitute of Reproductive Health, Center for Reproductive Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China.
Ai-Hua LiaoInstitute of Reproductive Health, Center for Reproductive Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China.
Huazhong University of Science and Technology · CNWayne State University · US

Funding

Mechanisms of trophoblast-induced immune modulationR01AI145829 · NIAID · WAYNE STATE UNIVERSITY · PI MOR, GIL G · 2019 to 2023
$1.9M
Impact of benzene-induced MIA on fetal T cell developmentR01HD111146 · NICHD · WAYNE STATE UNIVERSITY · PI MOR, GIL G · 2023 to 2025
$1.1M
NIAID NIH HHS R01 AI145829NICHD NIH HHS R01 HD111146
6 · The paper itself

Abstract

A successful pregnancy requires the maternal immune system to tolerate an allogeneic fetus. The incidence of preeclampsia and other complications related to impaired fetal tolerance is lower during the second pregnancy than during the first pregnancy. At the same time, compared with normal pregnant women in the previous pregnancy, patients with pregnancy complications in the previous pregnancy also have an increased risk of the disease when they become pregnant again. This difference may be related to the immunological memory of pregnancy. Regulatory T cells (Tregs) are immunosuppressive CD4

Indexed as

Immunologic MemoryT-Lymphocytes, RegulatoryAnimalsAntigensFemaleFetusHumansImmune ToleranceMicePregnancyAntigensgestational diabetes mellitusmemorypreeclampsiapregnancyregulatory T cells

Identifiers

PMID35414772
PMCPMC8990478
OpenAlexW4226085289

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.