Evidence map›Paper›PMID 35414722›Full record

GuidelinePathologica2022

Pathological examination of breast cancer samples before and after neoadjuvant therapy: recommendations from the Italian Group for the Study of Breast Pathology - Italian Society of Pathology (GIPaM-SIAPeC).

Nicola Fusco, Antonio Rizzo, Leopoldo Costarelli, Alfredo Santinelli, Bruna Cerbelli, Cristian Scatena, Ettore Macrì, Francesca Pietribiasi, Giulia d'Amati, Anna Sapino and 1 more

Open access · diamondAbstract readGuideline
In one paragraph

Guideline in Pathologica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 1 country.

Nicola FuscoDivision of Pathology, IEO, European Institute of Oncology IRCCS Milan, Italy.
Antonio RizzoDivision of Pathology, Humanitas Cancer Center, Catania, Italy.
Leopoldo CostarelliDepartment of Pathology, San Giovanni-Addolorata Hospital, Rome Italy.
Alfredo SantinelliAnatomic Pathology, Azienda Ospedaliera Ospedali Riuniti Marche Nord, Pesaro, Italy.
Bruna CerbelliDepartment of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Rome, Italy.
Cristian ScatenaDepartment of Laboratory Medicine, Pisa University Hospital, Anatomic Pathology 1 Universitaria, Pisa, Italy.
Ettore MacrìDivision of Pathology, San Martino Hospital, Belluno, Italy.
Francesca PietribiasiDivision of Pathology, Santa Croce Hospital, Moncalieri (TO), Italy.
Giulia d'AmatiDepartment of Radiological, Oncological and Pathological Sciences, ‹Sapienza› University of Rome, Rome, Italy.
Anna SapinoCandiolo Cancer Institute, FPO-IRCCS Candiolo, (TO), Italy.
Isabella CastellanoDepartment of Medical Sciences, University of Turin, Italy.
Sapienza University of Rome · ITUniversity of Turin · ITAzienda Ospedaliera San Giovanni Addolorata · ITAzienda Ospedaliera Universitaria Pisana · ITHumanitas University · ITOspedale Policlinico San Martino · ITOspedali Riuniti Marche Nord · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neoadjuvant therapy (NAT) in breast cancer is administered to downstage the tumor, de-escalate surgery, and provide prognostic information that can be used to tailor subsequent adjuvant therapy. In this respect, the pathological evaluation of both pre-NAT biopsies and post-NAT surgical specimens is crucial to precisely assess the treatment response. With the increasing possibilities of NAT protocols and the rising number of eligible patients, it has become extremely important to standardize the pathological response assessment. Here, we provide an update on the recommendations of the Italian Group for the Study of Breast Pathology - the Italian Society of Pathology (GIPaM-SIAPeC) for the analysis of breast cancer samples before and after NAT.

Indexed as

Breast NeoplasmsNeoadjuvant TherapyAntineoplastic Combined Chemotherapy ProtocolsBreastFemaleHumansPrognosisbiomarkersbreast cancerneoadjuvant therapypathological response

Identifiers

PMID35414722
PMCPMC9248246
OpenAlexW4223480919

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.