Evidence map›Paper›PMID 35414553›Full record

ArticleBMJ open2022

Assessing cardiometabolic parameter monitoring in inpatients taking a second-generation antipsychotic: The CAMI-SGA study - a cross-sectional study.

Jennifer Fontaine, Evelyn Chin, Jean-François Provencher, Anthony Rainone, Dana Wazzan, Carmella Roy, Soham Rej, Marie Lordkipanidze, Vincent Dagenais-Beaulé

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jennifer FontaineDepartment of Pharmacy, Jewish General Hospital, Montreal, Quebec, Canada.
Evelyn ChinDepartment of Pharmacy, Jewish General Hospital, Montreal, Quebec, Canada.
Jean-François ProvencherFaculté de Pharmacie, Université de Montréal, Montreal, Québec, Canada.
Anthony RainoneFaculté de Pharmacie, Université de Montréal, Montreal, Québec, Canada.
Dana WazzanDepartment of Pharmacy, Jewish General Hospital, Montreal, Quebec, Canada.
Carmella RoyPsychiatry, Jewish General Hospital, Montreal, Quebec, Canada.
Soham RejPsychiatry, Jewish General Hospital, Montreal, Quebec, Canada.
Marie LordkipanidzeFaculté de Pharmacie, Université de Montréal, Montreal, Québec, Canada.
Vincent Dagenais-BeauléDepartment of Pharmacy, Jewish General Hospital, Montreal, Quebec, Canada vdagenaisbeaule@jgh.mcgill.ca.ORCID 0000-0002-8526-857X
Jewish General Hospital · CAMcGill University Health Centre · CAMontreal Heart Institute · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aims to determine the proportion of initial cardiometabolic assessment and its predicting factors in adults with schizophrenia, bipolar disorder or other related diagnoses for whom a second-generation antipsychotic was prescribed in the hospital setting.

designCross-sectional study.

settingThe psychiatry unit of a Canadian tertiary care teaching hospital in Montreal, Canada.

participants402 patients with aforementioned disorders who initiated, restarted or switched to one of the following antipsychotics: clozapine, olanzapine, risperidone, paliperidone or quetiapine, between 2013 and 2016. PRIMARY OUTCOME MEASURES: We assessed the proportion of cardiometabolic parameters monitored. SECONDARY OUTCOME MEASURES: We identified predictors that influence the monitoring of cardiometabolic parameters and we assessed the proportion of adequate interventions following the screening of uncontrolled blood pressure and fasting glucose or glycated haemoglobin (HbA1c) results.

resultsOnly 37.3% of patients received monitoring for at least three cardiometabolic parameters. Blood pressure was assessed in 99.8% of patients; lipid profile in 24.4%; fasting glucose or HbA1c in 33.3% and weight or body mass index in 97.8% of patients while waist circumference was assessed in 4.5% of patients. For patients with abnormal blood pressure and glycaemic values, 42.3% and 41.2% subsequent interventions were done, respectively. The study highlighted the psychiatric diagnosis (substance induced disorder OR 0.06 95% CI 0.00 to 0.44), the presence of a court-ordered treatment (OR 0.79 95% CI 0.35 to 1.79) and the treating psychiatrist (up to OR 34.0 95% CI 16.2 to 140.7) as predictors of cardiometabolic monitoring.

conclusionsThis study reports suboptimal baseline cardiometabolic monitoring of patients taking an antipsychotic in a Canadian hospital. Optimising collaboration within a multidisciplinary team may increase cardiometabolic monitoring.

Indexed as

Antipsychotic AgentsCardiovascular DiseasesAdultBenzodiazepinesBlood GlucoseCanadaCross-Sectional StudiesGlycated HemoglobinHumansInpatientsQuetiapine FumarateAntipsychotic AgentsBenzodiazepinesBlood GlucoseGlycated HemoglobinQuetiapine Fumarateantipsychotic agentsbipolar disordercardiometabolic side effectsdrug-related side effects and adverse reactionsguideline adherenceschizophrenia

Identifiers

PMID35414553
PMCPMC9006820
OpenAlexW4223449912

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.