ArticleBiology of sex differences2022
Overall and sex-specific risk factors for subjective cognitive decline: findings from the 2015-2018 Behavioral Risk Factor Surveillance System Survey.
Article in Biology of sex differences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Cognitive and immunological effects of yoga compared to memory training in older women at risk for alzheimer's disease.Translational psychiatry · 2024Trial
- Age and sex differences in cognitive performance in people with subjective cognitive decline and associated worry: Findings from the Canadian Longitudinal Study on Aging.Journal of neuropsychology · 2026Article
- A world view: Considerations of sociocultural diversity in the study of subjective cognitive decline in Alzheimer's disease and related dementias.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Prevalence and associated factors of subjective cognitive decline (SCD Plus): a cross-sectional analysis of three population-based European cohorts.Alzheimer's research & therapy · 2026Article
- The relationship between Subjective Cognitive Decline-Financial Interference and excess Spending in Older Adults With and Without Early Memory Loss.Journal of ageing and longevity · 2025Article
- The relationship between social networks and subjective cognitive decline in Chinese younger older adults: the mediating effect of self-perception of aging.BMC public health · 2025Article
- Towards characterizing subjective cognitive decline in older adults.Journal of Alzheimer's disease : JAD · 2025Article
- Factors affecting subjective cognitive decline: an automated machine learning approach.Frontiers in neuroscience · 2025Article
- Vascular risk factor associations with subjective cognitive decline and mild behavioural impairment.Brain communications · 2025Article
- Intersectionality of gender with social determinants of health and asymptomatic Alzheimer's disease neuropathology.Journal of Alzheimer's disease : JAD · 2024Article
- Herpes zoster and long-term risk of subjective cognitive decline.Alzheimer's research & therapy · 2024Article
- Cognitive Symptoms Across Diverse Cancers.JAMA network open · 2024Article
- Psychometric properties and normative data of the Italian version of the Cognitive Function at Work Questionnaire: a screening tool for detecting subjective cognitive complaints at work.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- Prevalence and risk factors of subjective cognitive decline in older adults in Baotou, China: a cross-sectional study.Frontiers in aging neuroscience · 2024Article
- Improvement of frailty prevalence: difference in factors affecting frailty prevalence among 75 year-old individuals between 2006 and 2019.Journal of physical therapy science · 2023Article
- Associations of Depressive Symptoms with Subjective Cognitive Decline in Elderly People-A Cross-Sectional Analysis from the AgeWell.de-Study.Journal of clinical medicine · 2023Article
- Xanthohumol improves cognitive impairment by regulating miRNA-532-3p/Mpped1 in ovariectomized mice.Psychopharmacology · 2023Article
- Mental Fatigue Is Associated with Subjective Cognitive Decline among Older Adults.Brain sciences · 2023Article
- How preclinical models of menopause can inform clinical care: A focus on midlife and reciprocal communication between clinical and preclinical science.Current opinion in endocrine and metabolic research · 2023Article
- Social determinants of health, genetic biomarkers, and cognitive function in Chinese older adults with subjective cognitive decline and mild cognitive impairment: A cross-sectional analysis.Journal of Alzheimer's disease reportsArticle
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Abstract
backgroundPrior research indicates that at least 35% of Alzheimer's disease and related dementia risk may be amenable to prevention. Subjective cognitive decline is often the first indication of preclinical dementia, with the risk of subsequent Alzheimer's disease in such individuals being greater in women than men. We wished to understand how modifiable factors are associated with subjective cognitive decline, and whether differences exist by sex.
methodsData were collected from men and women (45 years and older) who completed the U.S. Behavioral Risk Factor Surveillance System Cognitive Decline Module (2015-2018), n = 216,838. We calculated population-attributable fractions for subjective cognitive decline, stratified by sex, of the following factors: limited education, deafness, social isolation, depression, smoking, physical inactivity, obesity, hypertension, and diabetes. Our models were adjusted for age, race, income, employment, marital and Veteran status, and accounted for communality among risk factors.
resultsThe final study sample included more women (53.7%) than men, but both had a similar prevalence of subjective cognitive decline (10.6% of women versus 11.2% of men). Women and men had nearly equivalent overall population-attributable fractions to explain subjective cognitive decline (39.7% for women versus 41.3% for men). The top three contributing risk factors were social isolation, depression, and hypertension, which explained three-quarters of the overall population-attributable fraction.
conclusionsWhile we did not identify any differences in modifiable factors between men and women contributing to subjective cognitive decline, other factors including reproductive or endocrinological health history or biological factors that interact with sex to modify risk warrant further research.
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