Evidence map›Paper›PMID 35414016›Full record

ReviewNature cell biology2022

Exploring the expanding universe of small RNAs.

Junchao Shi, Tong Zhou, Qi Chen

Abstract readReview
In one paragraph

Review in Nature cell biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 139 papers.

0numbers the graph read from it
0cells of the map it votes in
139citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

139 citing papers in PubMed.

  1. Article
  2. In silico unwinding ofRNA biology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Droplet Digital CRISPR for Nucleic Acid Detection.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  19. Review
  20. Dissecting the small RNA code of inflammatory bowel disease.Molecular medicine (Cambridge, Mass.) · 2026
    Article

79 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Junchao ShiDivision of Biomedical Sciences, School of Medicine, University of California, Riverside, CA, USA.ORCID http://orcid.org/0000-0002-1548-5069
Tong ZhouDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, NV, USA. tongz@med.unr.edu.ORCID http://orcid.org/0000-0003-2361-1931
Qi ChenDivision of Biomedical Sciences, School of Medicine, University of California, Riverside, CA, USA. qi.chen@medsch.ucr.edu.ORCID http://orcid.org/0000-0001-6353-9589

Funding

Mechanism Underlying the Transduction of Epimutations from the Soma to the Male GermlineP50HD098593 · NICHD · UNIVERSITY OF NEVADA RENO · PI YAN, WEI · 2019 to 2024
$7.2M
Sperm tsRNAs/rsRNAs and their RNA modifications in diet-induced epigenetic inheritanceR01HD092431 · NICHD · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Qi Chen, David S Milstone · 2017 to 2026
$3.5M
Decoding the signature of sperm RNA & RNA modification of environmental stressors on the intergenerational transmission of metabolic phenotypesR01ES032024 · NIEHS · UNIVERSITY OF UTAH · PI CHEN, QI, ZHOU, TONG · 2020 to 2024
$2.1M
NICHD NIH HHS P50 HD098593NICHD NIH HHS R01 HD092431NIEHS NIH HHS R01 ES032024
6 · The paper itself

Abstract

The world of small noncoding RNAs (sncRNAs) is ever-expanding, from small interfering RNA, microRNA and Piwi-interacting RNA to the recently emerging non-canonical sncRNAs derived from longer structured RNAs (for example, transfer, ribosomal, Y, small nucleolar, small nuclear and vault RNAs), showing distinct biogenesis and functional principles. Here we discuss recent tools for sncRNA identification, caveats in sncRNA expression analysis and emerging methods for direct sequencing of sncRNAs and systematic mapping of RNA modifications that are integral to their function.

Indexed as

MicroRNAsRNA, Small UntranslatedRNA, Small InterferingMicroRNAsRNA, Small InterferingRNA, Small Untranslated

Identifiers

PMID35414016
PMCPMC9035129

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.