Evidence map›Paper›PMID 35413931›Full record

ArticleTrials2022

Effect of novel training to normalize altered finger force direction post-stroke: study protocol for a double-blind randomized controlled trial.

Na Jin Seo, Derek G Kamper, Viswanathan Ramakrishnan, Jillian B Harvey, Christian Finetto, Christian Schranz, Gabrielle Scronce, Kristen Coupland, Keith Howard, Jenna Blaschke and 4 more

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03995069 (Novel Training Environment to Normalize Altered Finger Force Direction Post Stroke), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03995069 nacompletednot on this map

Novel Training Environment to Normalize Altered Finger Force Direction Post Stroke

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2020 to 2024Enrolled51ConditionsStrokeArms3D, 1D
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Na Jin SeoRalph H. Johnson VA Medical Center, Charleston, SC, USA. NaJin.Seo@va.gov.ORCID http://orcid.org/0000-0001-6446-5905
Derek G KamperJoint Department of Biomedical Engineering, North Carolina State University, University of North Carolina at Chapel Hill, Chapel Hill, NC, Raleigh, USA.ORCID https://orcid.org/0000-0001-9048-4106
Viswanathan RamakrishnanDepartment of Public Health Sciences, Medical University of South Carolina, 135 Cannon St, Charleston, SC, 29425, USA.ORCID https://orcid.org/0000-0002-4098-0539
Jillian B HarveyDepartment of Healthcare Leadership and Management, Medical University of South Carolina, 151B Rutledge Ave, MSC 962, Charleston, SC, 29425, USA.ORCID https://orcid.org/0000-0002-6814-8226
Christian FinettoDepartment of Health Sciences and Research, Medical University of South Carolina, 77 President St, MSC 700, Charleston, SC, 29425, USA.ORCID https://orcid.org/0000-0003-0520-2034
Christian SchranzDepartment of Health Sciences and Research, Medical University of South Carolina, 77 President St, MSC 700, Charleston, SC, 29425, USA.ORCID https://orcid.org/0000-0003-1102-7180
Gabrielle ScronceDepartment of Health Sciences and Research, Medical University of South Carolina, 77 President St, MSC 700, Charleston, SC, 29425, USA.ORCID https://orcid.org/0000-0002-3861-1371
Kristen CouplandDepartment of Health Sciences and Research, Medical University of South Carolina, 77 President St, MSC 700, Charleston, SC, 29425, USA.
Keith HowardDepartment of Health Sciences and Research, Medical University of South Carolina, 77 President St, MSC 700, Charleston, SC, 29425, USA.
Jenna BlaschkeDivision of Occupational Therapy, Department of Rehabilitation Sciences, Medical University of South Carolina, 151B Rutledge Ave, MSC 962, Charleston, SC, 29425, USA.
Adam BakerDepartment of Health Sciences and Research, Medical University of South Carolina, 77 President St, MSC 700, Charleston, SC, 29425, USA.
Caitlyn MeinzerDepartment of Public Health Sciences, Medical University of South Carolina, 135 Cannon St, Charleston, SC, 29425, USA.
Craig A VelozoDivision of Occupational Therapy, Department of Rehabilitation Sciences, Medical University of South Carolina, 151B Rutledge Ave, MSC 962, Charleston, SC, 29425, USA.
Robert J AdamsDepartment of Neurology, Medical University of South Carolina, 96 Jonathan Lucas St, MSC 606, Charleston, SC, 29425, USA.
Medical University of South Carolina · USUniversity of North Carolina at Chapel Hill · US

Funding

Treating Depression and Enhancing Locomotor Recovery Post-strokeP20GM109040 · NIGMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI KAUTZ, STEVEN A. · 2014 to 2024
$23.5M
Novel training environment to normalize altered finger force direction post strokeI01RX003066 · VA · RALPH H JOHNSON VA MEDICAL CENTER · PI SEO, NA JIN · 2019 to 2023
–
NIGMS NIH HHS P20 GM109040RRD VA I01 RX003066U.S. Department of Veterans Affairs I01RX003066
6 · The paper itself

Abstract

backgroundFunctional task performance requires proper control of both movement and force generation in three-dimensional space, especially for the hand. Control of force in three dimensions, however, is not explicitly treated in current physical rehabilitation. To address this gap in treatment, we have developed a tool to provide visual feedback on three-dimensional finger force. Our objective is to examine the effectiveness of training with this tool to restore hand function in stroke survivors.

methodsDouble-blind randomized controlled trial. All participants undergo 18 1-h training sessions to practice generating volitional finger force of various target directions and magnitudes. The experimental group receives feedback on both force direction and magnitude, while the control group receives feedback on force magnitude only. The primary outcome is hand function as measured by the Action Research Arm Test. Other outcomes include the Box and Block Test, Stroke Impact Scale, ability to direct finger force, muscle activation pattern, and qualitative interviews. DISCUSSION: The protocol for this clinical trial is described in detail. The results of this study will reveal whether explicit training of finger force direction in stroke survivors leads to improved motor control of the hand. This study will also improve the understanding of neuromuscular mechanisms underlying the recovery of hand function.

trial registrationClinicalTrials.gov NCT03995069 . Registered on June 21, 2019.

Indexed as

StrokeStroke RehabilitationHandHumansRandomized Controlled Trials as TopicRecovery of FunctionTreatment OutcomeUpper ExtremityBiofeedbackControlEMGGrip forceHand functionParalysisPhysical rehabilitationRandomized controlled trialStrokeUpper extremity

Identifiers

PMID35413931
PMCPMC9003156
OpenAlexW4223442966

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.