ArticleBMC public health2022
Prioritizing COVID-19 vaccination efforts and dose allocation within Madagascar.
Article in BMC public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Evaluating COVID-19 vaccination policy in Québec (Canada) using a data-driven dynamic transmission model.PLoS computational biology · 2025Article
- Optimizing vaccine uptake in sub-Saharan Africa: a collaborative COVID-19 vaccination campaign in Madagascar using an adaptive approach.Implementation science : IS · 2025Article
- Assessing the Economic Benefit of Mass COVID-19 Vaccination Program in Iran: A Real-World Modeling Study.International journal of health policy and management · 2025Article
- Drivers of COVID-19 vaccine uptake among rural populations in Madagascar: a cross-sectional study.BMC public health · 2024Article
- Inferring COVID-19 testing and vaccination behavior from New Jersey testing data.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Covid19Vaxplorer: A free, online, user-friendly COVID-19 vaccine allocation comparison tool.PLOS global public health · 2024Article
- COVID-19 vaccination strategies in settings with limited rollout capacity: a mathematical modelling case study in Sierra Leone.BMC public health · 2023Article
- Covid19Vaxplorer: a free, online, user-friendly COVID-19 Vaccine Allocation Comparison Tool.medRxiv : the preprint server for health sciences · 2023Article
- Assessing the Influence of COVID-19 Vaccination Coverage on Excess Mortality across 178 Countries: A Cross-Sectional Study.Vaccines · 2023Article
- Excess mortality associated with the COVID-19 pandemic during the 2020 and 2021 waves in Antananarivo, Madagascar.BMJ global health · 2023Article
- High seroprevalence of SARS-CoV-2 in Burkina-Faso, Ghana and Madagascar in 2021: a population-based study.BMC public health · 2022Article
- Epidemiological impact and cost-effectiveness analysis of COVID-19 vaccination in Kenya.BMJ global health · 2022Article
- Optimal control of the spatial allocation of COVID-19 vaccines: Italy as a case study.PLoS computational biology · 2022Article
- Full GenomeFrontiers in public health · 2022Article
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10 authors.
Funding
Abstract
backgroundWhile mass COVID-19 vaccination programs are underway in high-income countries, limited availability of doses has resulted in few vaccines administered in low and middle income countries (LMICs). The COVID-19 Vaccines Global Access (COVAX) is a WHO-led initiative to promote vaccine access equity to LMICs and is providing many of the doses available in these settings. However, initial doses are limited and countries, such as Madagascar, need to develop prioritization schemes to maximize the benefits of vaccination with very limited supplies. There is some consensus that dose deployment should initially target health care workers, and those who are more vulnerable including older individuals. However, questions of geographic deployment remain, in particular associated with limits around vaccine access and delivery capacity in underserved communities, for example in rural areas that may also include substantial proportions of the population.
methodsTo address these questions, we developed a mathematical model of SARS-CoV-2 transmission dynamics and simulated various vaccination allocation strategies for Madagascar. Simulated strategies were based on a number of possible geographical prioritization schemes, testing sensitivity to initial susceptibility in the population, and evaluating the potential of tests for previous infection.
resultsUsing cumulative deaths due to COVID-19 as the main outcome of interest, our results indicate that distributing the number of vaccine doses according to the number of elderly living in the region or according to the population size results in a greater reduction of mortality compared to distributing doses based on the reported number of cases and deaths. The benefits of vaccination strategies are diminished if the burden (and thus accumulated immunity) has been greatest in the most populous regions, but the overall strategy ranking remains comparable. If rapid tests for prior immunity may be swiftly and effectively delivered, there is potential for considerable gain in mortality averted, but considering delivery limitations modulates this.
conclusionAt a subnational scale, our results support the strategy adopted by the COVAX initiative at a global scale.
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