Evidence map›Paper›PMID 35413834›Full record

ArticleEnvironmental health : a global access science source2022

Air pollution and biomarkers of cardiovascular disease and inflammation in the Malmö Diet and Cancer cohort.

Mehjar Azzouz, Yiyi Xu, Lars Barregard, Björn Fagerberg, Bengt Zöller, Peter Molnár, Anna Oudin, Mårten Spanne, Gunnar Engström, Leo Stockfelt

Open access · goldAbstract read
In one paragraph

Article in Environmental health : a global access science source, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Differential effects of neighborhood ambient PMInternational journal of health geographics · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Mehjar AzzouzOccupational and Environmental Medicine, School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. mehjar.azzouz@gmail.com.ORCID 0000-0002-1988-2010
Yiyi XuOccupational and Environmental Medicine, School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Lars BarregardOccupational and Environmental Medicine, School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Björn FagerbergDepartment of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Bengt ZöllerCenter for Primary Health Care Research, Lund University/Region Skåne, Malmö, Sweden.
Peter MolnárOccupational and Environmental Medicine, School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Anna OudinOccupational and Environmental Medicine, Department for Laboratory Medicine, Lund University, Lund, Sweden.
Mårten SpanneEnvironment Department, City of Malmö, Malmö, Sweden.
Gunnar EngströmDepartment of Clinical Sciences in Malmö, CRC, Lund University, Lund, Sweden.
Leo StockfeltOccupational and Environmental Medicine, School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
University of Gothenburg · SELund University · SESahlgrenska University Hospital · SEMalmö Municipality · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAir pollution is associated with increased risk of cardiovascular disease, possibly through chronic systemic inflammation that promotes the progression of atherosclerosis and the risk of cardiovascular events. This study aimed to investigate the associations between air pollution and established biomarkers of inflammation and cardiovascular disease.

methodsThe Cardiovascular Subcohort of the Malmö Diet and Cancer cohort includes 6103 participants from the general population of Malmö, Sweden. The participants were recruited 1991-1994. Annual mean residential exposure to particulate matter < 2.5 and < 10 μm (PM

resultsThe mean annual exposure levels in the cohort were only slightly or moderately above the new WHO guidelines of 5 μg/m

conclusionLong-term residential exposure to moderate levels of particulate air pollution was associated with several biomarkers of inflammation and cardiovascular disease. This supports inflammation as a mechanism behind the association between air pollution and cardiovascular disease.

Indexed as

Air PollutantsAir PollutionCardiovascular DiseasesNeoplasms1-Alkyl-2-acetylglycerophosphocholine EsteraseBiomarkersCeruloplasminC-Reactive ProteinCross-Sectional StudiesDietEnvironmental ExposureHaptoglobinsHumansInflammationOrosomucoidParticulate Matter1-Alkyl-2-acetylglycerophosphocholine EsteraseAir PollutantsBiomarkersCeruloplasminC-Reactive ProteinHaptoglobinsOrosomucoidParticulate MatterReceptors, Urokinase Plasminogen ActivatorAir pollutionBiomarkersCardiovascular diseaseC-reactive proteinInflammationParticulate matter

Identifiers

PMID35413834
PMCPMC9004064
OpenAlexW4223509568

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.