ReviewAnaesthesiology intensive therapy2022
Methods of assessing fluid responsiveness in septic shock patients: a narrative review.
Review in Anaesthesiology intensive therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Non-Linear Threshold Effect of Dynamic Estimated Plasma Volume Status on Revealing In-Hospital Mortality Risk in Sepsis.The Kaohsiung journal of medical sciences · 2026Article
- Impact of central venous pressure trajectories on prognosis in ICU patients with sepsis.Scientific reports · 2026Article
- Septic shock in the era of precision medicine: rethinking fluids, vasopressors, and immunomodulation.Frontiers in medicine · 2026Review
- Testosterone and androgen receptor pathway modulation in sepsis: immunometabolic mechanisms and therapeutic implications - a scoping review.Frontiers in endocrinology · 2026Article
- From Fluid Responsiveness to Prognosis: The Emerging Role of Point-of-Care Echocardiography in Sepsis.Diagnostics (Basel, Switzerland) · 2025Review
- Intra-abdominal sepsis in critically ill surgical patients: the relationship between cumulative fluid balance and serum sodium and chloride levels and in-hospital mortality.Frontiers in medicine · 2025Article
- Volume assessment comparing femoral vein and inferior vena cava among chest pain patients presenting to the emergency department.International journal of emergency medicine · 2024Article
- PiCCO or Cardiac Ultrasound? Which Is Better for Hemodynamic Monitoring in ICU?Medicina (Kaunas, Lithuania) · 2024Review
- Advances in Shock Management and Fluid Resuscitation in Children.Indian journal of pediatrics · 2023Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A growing body of evidence shows that some septic patients experience fluid overload, which leads to an increased number of serious complications and death. This is because the majority of septic patients are fluid non-responders. Therefore, a reliable distinction of which patient would benefit from fluid boluses is crucial in current sepsis mana-gement. Several methods used to assess fluid responsiveness have been developed. The principle of "dynamic" measurements (in contrast to static indices such as central venous pressure) involves the induction of a change in cardiac preload and the measurement of its effect on stroke volume. Dynamic methods are based on either heart-lung interaction during mechanical ventilation or on an assessment of change in cardiac stroke volume in response to fluid provocative stimuli such as rapid fluid administration, passive leg raising, or the end-expiratory occlusion test. Most dynamic measurements are easy to perform and interpret as well as being available at the bedside. However, they vary in their invasiveness, difficulty in performance, reliability, and limitations. In this study, we provide an overview of various methods for assessing fluid responsiveness and indicate those that potentially lead to haemodynamically guided fluid restrictive treatment that would prevent fluid overload in septic patients.
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