Evidence map›Paper›PMID 35413786›Full record

Observational studyAnaesthesiology intensive therapy2022

Integrated ultrasound protocol in predicting weaning success and extubation failure: a prospective observational study.

Riddhi Kundu, Dalim Baidya, Rahul Anand, Souvik Maitra, Kapil Soni, Rajeshwari Subramanium

Abstract readObservational Study
In one paragraph

Observational study in Anaesthesiology intensive therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Lung Ultrasound Score: Does It Really Predict Extubation Failure?Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2023
    Article
  8. Commentary on "Prediction of Successful Spontaneous Breathing Trial and Extubation of Trachea by Lung Ultrasound in Mechanically Ventilated Patients in Intensive Care Unit".Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2023
    Article
  9. Article
  10. Article
  11. Diaphragmatic Rapid Shallow Breathing Index: A Simple Tool to Give more Power to Predict Weaning?Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2022
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Riddhi KunduDepartment of Critical Care Medicine, Manipal Hospitals, New Delhi, India.
Dalim BaidyaDepartment of Anaesthesiology, Pain Medicine, and Critical Care, All India Institute of Medical Sciences(AIIMS), New Delhi, India.
Rahul AnandDepartment of Anaesthesiology, Pain Medicine, and Critical Care, All India Institute of Medical Sciences(AIIMS), New Delhi, India.
Souvik MaitraDepartment of Anaesthesiology, Pain Medicine, and Critical Care, All India Institute of Medical Sciences(AIIMS), New Delhi, India.
Kapil SoniDepartment of Trauma and Critical Care, All India Institute of Medical Sciences(AIIMS), New Delhi, India.
Rajeshwari SubramaniumDepartment of Anaesthesiology, Pain Medicine, and Critical Care, All India Institute of Medical Sciences(AIIMS), New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDifficulty in weaning from mechanical ventilation is encountered in appro-ximately 20% of patients in the intensive care unit. We assessed the utility of a combined lung, diaphragmatic, and cardiac ultrasound protocol to predict extubation failure. MATERIAL: All patients extubated following a successful spontaneous breathing trial (SBT) were included in the study. Lung ultrasonography score (LUS), diaphragmatic thickness fraction (DTF), changes in velocity time integral (VTI) to passive leg raise at the beginning of SBT, and change in LUS following SBT were recorded.

resultsA total of 60 patients who underwent successful SBT were included in the study. Twenty-seven patients required either non-invasive or invasive mechanical ventilation during the next 48 hours and were classified as weaning failure (Group F). The remaining 33 patients were designated as weaning success (Group S). Compared to group S, patients in Group F had significantly longer ICU length of stay (6.96 ± 4.30 days vs. 11.66 ± 3.85 days, P < 0.001), higher LUS change during SBT (1 [0-2] vs. 2 [1-4], P < 0.001), lower DTF (30.87 ± 5.32 vs. 27.88 ± 6.24, P = 0.04), and showed lower VTI increment to PLR (13.63 ± 3.44 vs. 9.11 ± 4.59, P < 0.001). Using a binary logistic regression model, DTF < 26% (odds ratio 6.20, 95% CI: 1.06-36.04) and VTI change to PLR < 10.2% (odds ratio 6.16, 95% CI: 1.14-33.13) were found to be significant predictors of weaning failure (P < 0.05). The AUROC for VTI and DTF for predicting weaning failure were 0.79 and 0.64, respectively.

conclusionsAn integrated ultrasound protocol using a combination of lung, diaphragm, and cardiac sonography was a reliable predictor of weaning failure.

Indexed as

Airway ExtubationVentilator WeaningDiaphragmHumansProspective StudiesRespiration, ArtificialUltrasonographymechanical ventilationultrasound.weaning

Identifiers

PMID35413786
PMCPMC10156490

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.