ArticleJournal of molecular and cellular cardiology2022
Preserved cardiac performance and adrenergic response in a rabbit model with decreased ryanodine receptor 2 expression.
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Article in Journal of molecular and cellular cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
What it found
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Who cites it
12 citing papers in PubMed, 14 citations in OpenAlex.
- Type-1 Ryanodine Receptor Plays an Important Role in Cardiac Hypertrophy and Heart Failure by Increasing Type-2 Ryanodine Receptor-Mediated Calcium Release.International journal of molecular sciences · 2026Article
- Calcium release deficiency syndrome: an emerging ryanodinopathy.Frontiers in molecular biosciences · 2026Review
- Decreased RYR2 Cluster Size and Abnormal SR CaAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Preventing the phosphorylation of RyR2 at canonical sites reduces CaNature cardiovascular research · 2025Article
- Layer-specific proteomic analysis of human hearts in patients with sudden cardiac death.PloS one · 2025Article
- Early pathological mechanisms in a mouse model of heart failure with preserved ejection fraction.American journal of physiology. Heart and circulatory physiology · 2024Article
- Dual ablation of the RyR2-Ser2808 and RyR2-Ser2814 sites increases propensity for pro-arrhythmic spontaneous CaThe Journal of physiology · 2024Article
- Restoring Atrial T-Tubules Augments Systolic Ca Upon Recovery From Heart Failure.Circulation research · 2024Article
- Dynamin-related protein 1 is a critical regulator of mitochondrial calcium homeostasis during myocardial ischemia/reperfusion injury.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024Article
- Long-term efficacy and safety of cardiac genome editing for catecholaminergic polymorphic ventricular tachycardia.The journal of cardiovascular aging · 2024Article
- Clustering properties of the cardiac ryanodine receptor in health and heart failure.Journal of molecular and cellular cardiology · 2023Review
- Hypertrophic cardiomyopathy is characterized by alterations of the mitochondrial calcium uniporter complex proteins: insights from patients with aortic valve stenosis versus hypertrophic obstructive cardiomyopathy.Frontiers in pharmacology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 5 institutions in 3 countries.
Jingjing ZhengDepartment of Medicine and Cardiovascular Research Center, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA; Department of Forensic Pathology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Holly C DoogeDepartment of Medicine and Cardiovascular Research Center, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA.
Marta Pérez-HernándezLeon H Charney Division of Cardiology, New York University Grossman School of Medicine,. New York, NY, United States of America.
Yan-Ting ZhaoCenter for Arrhythmia Research, University of Michigan, Ann Arbor, MI, United States of America.
Xi ChenDepartment of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, United States of America.
Jonathan J HernandezDepartment of Pediatrics, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, United States of America.
Carmen R ValdiviaDepartment of Medicine and Cardiovascular Research Center, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA.
Julieta PalomequeCentro de Investigaciones Cardiovasculares, CCT-La Plata-CONICET, Facultad de Ciencias Médicas, UNLP, La Plata, Argentina.
Eli RothenbergInstitute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY, United States of America.
Mario DelmarLeon H Charney Division of Cardiology, New York University Grossman School of Medicine,. New York, NY, United States of America.
Héctor H ValdiviaDepartment of Medicine and Cardiovascular Research Center, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA.
Francisco J AlvaradoDepartment of Medicine and Cardiovascular Research Center, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA. Electronic address: falvarad@medicine.wisc.edu.
University of Wisconsin–Madison · USNew York University · USUniversity of Michigan–Ann Arbor · USCentro de Investigaciones Cardiovasculares · ARSun Yat-sen University · CN
Funding
Training In Cardiovascular Physiology & PharmacologyT32HL007444 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Ju Chen, Robert Scott Ross · 1985 to 2026
$11.1MRyanodine Receptors, Calcium-dependent Arrhythmias & HCMR01HL055438 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI VALDIVIA, HECTOR H · 1996 to 2023
$8.0MUCSD PRIDE Faculty Development Program in Cardiovascular SciencesR25HL145817 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Robert Scott Ross, Joann Trejo · 2019 to 2026
$3.3MRole of PKP2 in epicardial structure and functionR01HL136179 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI DELMAR, MARIO, MORLEY, GREGORY E · 2017 to 2020
$3.1MRole of desmosomes in cardiac electrical functionR01HL134328 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI DELMAR, MARIO, MORLEY, GREGORY E · 2016 to 2019
$2.6MMechanisms of calcium-induced arrhythmias in arrhythmogenic right ventricular cardiomyopathyR01HL161070 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI Francisco J Alvarado · 2022 to 2026
$1.9MNatural Agonists of Ryanodine Receptors: Structure-function Relationship and Antiarrhythmic PropertiesR01HL134344 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI VALDIVIA, HECTOR H · 2017 to 2020
$1.9MNHLBI NIH HHS R01 HL055438NHLBI NIH HHS R01 HL134328NHLBI NIH HHS R01 HL134344NHLBI NIH HHS R01 HL136179NHLBI NIH HHS R01 HL161070NHLBI NIH HHS R25 HL145817NHLBI NIH HHS T32 HL007444
Abstract
Ryanodine receptor 2 (RyR2) is an ion channel in the heart responsible for releasing into the cytosol most of the Ca
Indexed as
Adrenergic AgentsRyanodine Receptor Calcium Release ChannelAnimalsArrhythmias, CardiacCalciumCalcium SignalingExcitation Contraction CouplingMyocytes, CardiacRabbitsSarcoplasmic ReticulumAdrenergic AgentsCalciumRyanodine Receptor Calcium Release ChannelCalciumCardiomyocyteE-C CouplingRyanodine receptorRyR2
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.