ArticleCancer cell2022
Neoantigen-specific CD4
Open access · greenAbstract read
In one paragraph
Article in Cancer cell, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers.
0numbers the graph read from it
0cells of the map it votes in
104citing papers in PubMed
13.6field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
104 citing papers in PubMed, 135 citations in OpenAlex.
- Mobilizing antigen-presenting mast cells in anti-PD-1-refractory triple-negative breast cancer: a phase 2 trial.Nature medicine · 2025Trial
- Efficacy, safety and single-cell analysis of neoadjuvant immunochemotherapy in locally advanced oral squamous cell carcinoma: a phase II trial.Nature communications · 2025Trial
- CXCL13-expressing CD4Oncoimmunology · 2026Article
- Review
- Clonal sharing and plasticity of follicular CD4 + T cells across lymph nodes and tumors in non-small cell lung cancer.Nature communications · 2026Article
- Immune Spatial Organization Predicts Distant Metastasis Risk in Aggressive Localized Prostate Cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2026Article
- Circulating B cell and T cell activation states predict clinical outcomes in melanoma and reveal dynamic immune reinvigoration with checkpoint inhibitor immunotherapy.Journal for immunotherapy of cancer · 2026Article
- The Central Role of HLA Class II-Restricted Helper Neoantigen Vaccines in Cancer Immunotherapy.Cancers · 2026Review
- Transcriptomic analysis of tissue-resident memory T cells of the fallopian tube reveals a precursor immune surveillance network for ovarian cancer prevention.Nature communications · 2026Article
- The challenge and promise of studying human antigen-specific T cells.Nature reviews. Immunology · 2026Review
- Single cell and spatial atlas of macrophage and astrocyte interactions in glioblastoma.Discover oncology · 2026Article
- Hallmarks and correlates of effective adoptive cell immunotherapy for cancer.Nature reviews. Immunology · 2026Review
- Response of B Cells Specific for Polyomavirus-Derived Oncoprotein Is Predictive of Merkel Cell Carcinoma Tumor Control.Cancer immunology research · 2026Article
- PD-1 antibody-bound progenitor-exhausted CD8Nature communications · 2026Article
- Single-cell and spatial profiling reveal cDC2A-CXCL13Nature communications · 2026Article
- Cytotoxic CD4Signal transduction and targeted therapy · 2026Review
- Single-cell and spatial transcriptome profiling identifies cellular heterogeneity and immunosuppressive tumor microenvironment in inflammatory breast cancer.Journal of advanced research · 2026Article
- Intratumoral Three-Cell-Type Clusters Are a Conserved Feature of Endogenous Antitumor Immunity.Cancer immunology research · 2026Article
- Clinicopathologic, genetic and immune cell infiltration analysis of colorectal signet ring cell carcinoma with comparison to conventional adenocarcinoma.Journal of the National Cancer Center · 2026Article
- Immune landscape of melanoma: Tumor microenvironment, resistance mechanisms, and predictive biomarkers.World journal of clinical oncology · 2026Review
44 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
22 authors at 5 institutions in 2 countries.
Joshua R VeatchDepartment of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA, USA. Electronic address: jveatch@fredhutch.org.
Sylvia M LeeDepartment of Medical Oncology, University of Washington, Seattle, WA, USA.
Carolyn ShashaDepartment of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Naina SinghiDepartment of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Julia L SzetoDepartment of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Ata S MoshiriDepartment of Dermatology, University of Washington, Seattle, WA, USA.
Teresa S KimDepartment of Surgery, University of Washington, Seattle, WA, USA.
Kimberly SmytheDepartment of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Paul KongDepartment of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Matthew FitzgibbonDepartment of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Brenda JesernigDepartment of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Shailender BhatiaDepartment of Medical Oncology, University of Washington, Seattle, WA, USA.
Scott S TykodiDepartment of Medical Oncology, University of Washington, Seattle, WA, USA.
Evan T HallDepartment of Medical Oncology, University of Washington, Seattle, WA, USA.
David R ByrdDepartment of Surgery, University of Washington, Seattle, WA, USA.
John A ThompsonDepartment of Medical Oncology, University of Washington, Seattle, WA, USA.
Venu G PillarisettyDepartment of Surgery, University of Washington, Seattle, WA, USA.
Thomas DuhenEarle A. Chiles Research Institute, Providence Cancer Institute, Portland, OR, USA.
A McGarry HoughtonDepartment of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Evan NewellDepartment of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Raphael GottardoDepartment of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Stanley R RiddellDepartment of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Fred Hutch Cancer Center · USUniversity of Washington Medical Center · USUniversity of Washington · USCape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa · ZAProvidence Portland Medical Center · US
Funding
Project 4: Risk stratification for pulmonary nodules detected by CT imaging using plasma and imaging biomarkersP50CA228944 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI David MacPherson · 2019 to 2026
$19.6MCAREER DEVELOPMENT IN PEDIATRIC AND MEDICAL ONCOLOGYK12CA076930 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI DAVIDSON, NANCY ELLEN, MESHINCHI, SOHEIL · 1997 to 2025
$13.1MTARGETING ROR1 WITH CHIMERIC ANTIGEN RECEPTOR MODIFIED T CELLSR01CA114536 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Sylvain Simon · 2005 to 2026
$8.4MTherapeutic applications of CD4+ T cells specific for oncogenic driver mutationsK08CA241523 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI VEATCH, JOSHUA R · 2020 to 2024
$971kNCI NIH HHS K08 CA241523NCI NIH HHS K12 CA076930NCI NIH HHS P50 CA228944NCI NIH HHS R01 CA114536
Abstract
CD4
Indexed as
CD8-Positive T-LymphocytesMelanomaAnimalsAntigens, NeoplasmCD4-Positive T-LymphocytesHumansMacrophagesMiceTumor MicroenvironmentAntigens, NeoplasmbreastCD4CXCL13follicularmelanomaneoantigen
Identifiers
What OpenQuestion holds
Textmetadata
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Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.