Evidence map›Paper›PMID 35412954›Full record

ArticleBioengineered2022

lncRNA LINC01315 promotes malignancy of triple-negative breast cancer and predicts poor outcomes by modulating microRNA-876-5p/GRK5.

Yan Xiu, Shannan Cao, Ru Jiang, Yuming Zhou

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yan XiuMedical Clinical Laboratory, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, Shandong, China.
Shannan CaoMedical Clinical Laboratory, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, Shandong, China.
Ru JiangMedical Clinical Laboratory, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, Shandong, China.
Yuming ZhouMedical Clinical Laboratory, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, Shandong, China.
Binzhou University · CNBinzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triple-negative breast cancer (TNBC) is a malignant tumor that threatens women's health. Exploring novel development-associated biomarkers could help improve the survival rate of TNBC. This study evaluated the significance and mechanism of LINC01315 in TNBC progression aiming to identify a potential biomarker. There were 103 TNBC patients that provided clinical tissues in this study. The expression of LINC01315 was assessed by PCR and its association with clinical data was evaluated by statistical analyses. The

Indexed as

G-Protein-Coupled Receptor Kinase 5MicroRNAsRNA, Long NoncodingTriple Negative Breast NeoplasmsCell Line, TumorCell ProliferationFemaleHumansG-Protein-Coupled Receptor Kinase 5GRK5 protein, humanMicroRNAsMIRN876 microRNA, humanRNA, Long Noncodingdisease developmentlncRNA LINC01315miR-876-5pprognosisTriple-negative breast cancertumor progression

Identifiers

PMID35412954
PMCPMC9161853
OpenAlexW4223484571

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.