ArticleMolecular plant pathology2022
The apple FERONIA receptor-like kinase MdMRLK2 negatively regulates Valsa canker resistance by suppressing defence responses and hypersensitive reaction.
Article in Molecular plant pathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Insights into the roles of RALF peptides and CrRLK1L receptors in fruit ripening.The Plant journal : for cell and molecular biology · 2026Review
- An Apple Susceptibility-Related LRR Receptor-Like Kinase MdRLKT21 Activates Plant Immunity by Hijacking a Trans-Kingdom Fungal microRNA-Like RNA.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- A molecular perspective on the role of FERONIA in root growth, nutrient uptake, stress sensing and microbiome assembly.Journal of advanced research · 2025Review
- Jack of all trades: crosstalk between FERONIA signaling and hormone pathways.Journal of experimental botany · 2025Review
- RALF-FER, a master ligand‒receptor pair in plant health.Crop health · 2025Review
- MdVQ37 Negatively Regulates Apple Resistance to Valsa Canker via SA-Dependent and SA-Independent Pathways.Molecular plant pathology · 2025Article
- Advances in Protein Kinase Regulation of Stress Responses in Fruits and Vegetables.International journal of molecular sciences · 2025Review
- An effector essential for virulence of necrotrophic fungi targets plant HIRs to inhibit host immunity.Nature communications · 2024Article
- FERONIA homologs in stress responses of horticultural plants: current knowledge and missing links.Stress biology · 2024Review
- Small secreted effector protein from Fusarium sacchari suppresses host immune response by inhibiting ScPi21-induced cell death.Molecular plant pathology · 2024Article
- An efficient screening system of disease-resistant genes from wild apple, Malus sieversii in response to Valsa mali pathogenic fungus.Plant methods · 2023Article
- Lignin and Its Pathway-Associated Phytoalexins Modulate Plant Defense against Fungi.Journal of fungi (Basel, Switzerland) · 2022Review
- Regulation of immune complex formation and signalling by FERONIA, a busy goddess in plant-microbe interactions.Molecular plant pathology · 2022Review
- The apple FERONIA receptor-like kinase MdMRLK2 negatively regulates Valsa canker resistance by suppressing defence responses and hypersensitive reaction.Molecular plant pathology · 2022Article
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Authors and funding
8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Valsa canker, caused by the fungus Valsa mali, is one of the most destructive diseases of apple trees in China and other East Asian countries. The plant receptor-like kinase FERONIA is involved in plant cell growth, development, and immunity. However, little is known about the function of FERONIA in apple defence against V. mali. In this study, we found that MdMRLK2 was highly induced by V. mali in twigs of V. mali-susceptible Malus mellana but not in those of the resistant species Malus yunnaensis. 35S:MdMRLK2 apple plants showed compromised resistance relative to wild-type (WT) plants. Further analyses indicated that 35S:MdMRLK2 apple plants had enhanced abscisic acid (ABA) levels and reduced salicylic acid (SA) levels relative to the WT on V. mali infection. MdMRLK2 overexpression also suppressed polyphenol accumulation and inhibited the activities of phenylalanine ammonia-lyase (PAL), β-1,3-glucanase (GLU), and chitinase (CHT) during V. mali infection. Moreover, MdMRLK2 interacted with MdHIR1, a hypersensitive-induced response protein, and suppressed the MdHIR1-mediated hypersensitive reaction (HR), probably by impairing MdHIR1 self-interaction. Collectively, these findings demonstrate that overexpression of MdMRLK2 compromises Valsa canker resistance, probably by (a) altering ABA and SA levels, (b) suppressing polyphenol accumulation, (c) inhibiting PAL, GLU, and CHT activities, and (d) blocking MdHIR1-mediated HR by disrupting MdHIR1 self-interaction.
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