ArticleMicrobiology spectrum2022
Core Gut Microbiota of Shrimp Function as a Regulator to Maintain Immune Homeostasis in Response to WSSV Infection.
Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Physiological and Intestinal Microbiota Responses to the Feeding Stimulant Dimethyl-β-Propiothetin (DMPT) in Aquatic Animals-A Preliminary Study onAntioxidants (Basel, Switzerland) · 2026Article
- Dietary and water probiotics enhance immunity, modulate microbiota, and increase survival of Penaeus vannamei challenged with V. parahaemolyticus.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Article
- Article
- Host genome drives the microbiota enrichment of beneficial microbes in shrimp: exploring the hologenome perspective.Animal microbiome · 2025Article
- Changes in Muscle Quality and Gut Microbiota of Whiteleg Shrimp (Animals : an open access journal from MDPI · 2025Article
- Article
- Hemolymph microbiota and host immunity of crustaceans and mollusks.The ISME journal · 2025Review
- Symbiotic strategies: deciphering the role of gut microbiota in the nutrition and metabolism of fish and shellfish.Frontiers in cellular and infection microbiology · 2025Review
- Comparison of intestinal and environmental microbiota of the snapping shrimp (Frontiers in microbiology · 2025Article
- Transcriptome-wide identification and analysis reveals m6A regulation of metabolic reprogramming in shrimp (Marsupenaeus japonicus) under virus infection.BMC genomics · 2024Article
- Unveiling the Bacterial Community across the Stomach, Hepatopancreas, Anterior Intestine, and Posterior Intestine of Pacific Whiteleg Shrimp.Journal of microbiology and biotechnology · 2024Article
- Metagenomic Analyses Reveal Gut Microbial Profiles ofMicroorganisms · 2024Article
- Active Microbiota ofMicroorganisms · 2024Article
- Host-microbiome interaction in fish and shellfish: An overview.Fish and shellfish immunology reports · 2023Review
- Conserved organ-specific microbial assemblages in different populations of a terrestrial crab.Frontiers in microbiology · 2023Article
- The shared microbiome in mud crab (Frontiers in microbiology · 2023Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The gut microbiota is an integral part of the host and has a functional potential in host physiology. Numerous scientific efforts have opened new horizons in gut microbiota research and enhanced the understanding of host-microbe interactions in vertebrates. However, evidence on the association between the gut microbiota and immunity in invertebrates, especially in shrimp, which is an important aquatic animal, is limited. Herein, we conducted a comprehensive analysis based on 16S rRNA gene sequencing and liquid chromatography-coupled mass spectrometry (LC-MS) to investigate the correlation between them. Comparing the gut microbiota among the four different species of shrimp, we found huge variations and determined a core gut microbiota composed of 55 microbes. The environmental challenge of white spot syndrome virus (WSSV) infection led to changes in core microbial structures, but the alteration of core microbiota among different shrimp followed the same trend and showed immune-related function in the prediction of its metabolic potential. In metabolomic analysis, nine significantly upregulated metabolites found after viral infection indicated that they have antiviral potential. Moreover, we found a tight correlation between them and almost half of the core microbiota. These data demonstrate that these metabolites are responsible for maintaining the immune homeostasis of the host and prove the function of the gut microbiota and the related metabolome in antiviral immunity of shrimp.
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