Evidence map›Paper›PMID 35412154›Full record

ArticlePlanta2022

Morphogenesis, ultrastructure, and chemical profiling of trichomes in Artemisia argyi H. Lév. & Vaniot (Asteraceae).

Zhanhu Cui, Mengzhi Li, Xiaojing Han, Hongyan Liu, Chao Li, Huasheng Peng, Dahui Liu, Xianzhang Huang, Zhongyi Zhang

Abstract read
PubMed Publisher
In one paragraph

Article in Planta, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Pharmaceuticals (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. KoreanFrontiers in pharmacology · 2026
    Review
  9. Article
  10. Article
  11. Genome-Wide Identification and Analysis of theCurrent issues in molecular biology · 2025
    Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Zhanhu CuiCollege of Agriculture, Fujian Agriculture and Forestry University, Fuzhou, 350002, China.
Mengzhi LiHenan Province Key Laboratory of Zhang Zhongjing Formulae and Herbs for Immunoregulation, Nanyang Institute of Technology, Nanyang, 473004, China.
Xiaojing HanAnhui University of Chinese Medicine, Hefei, 230012, China.
Hongyan LiuExperimental Center, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China.
Chao LiHenan Province Key Laboratory of Zhang Zhongjing Formulae and Herbs for Immunoregulation, Nanyang Institute of Technology, Nanyang, 473004, China.
Huasheng PengAnhui University of Chinese Medicine, Hefei, 230012, China.
Dahui LiuHubei University of Chinese Medicine, Wuhan, 430065, China.
Xianzhang HuangHenan Province Key Laboratory of Zhang Zhongjing Formulae and Herbs for Immunoregulation, Nanyang Institute of Technology, Nanyang, 473004, China. nylgxyhxz@126.com.
Zhongyi ZhangCollege of Agriculture, Fujian Agriculture and Forestry University, Fuzhou, 350002, China. zyzhang@fafu.edu.cn.ORCID http://orcid.org/0000-0002-6375-2969
Nanyang Institute of Technology · CNAnhui University of Traditional Chinese Medicine · CNFujian Agriculture and Forestry University · CNHubei University of Chinese Medicine · CNShandong University of Traditional Chinese Medicine · CN

Funding

National Key Research and Development Program of China 2017YFC1700704Special Project for the Construction of Modern Agricultural Industrial Technology System CARS-21Young Scientists Fund 81803661
6 · The paper itself

Abstract

MAIN

conclusionGlandular trichomes of Artemisia argyi H. Lév. & Vaniot are the key tissues for the production of flavonoid and terpenoid metabolites. Artemisia argyi H. Lév. & Vaniot is an herbaceous perennial plant that has been widely used in traditional medicine for thousands of years. Glandular trichomes (GTs) and nonglandular trichomes (NGTs) have been reported on the leaf surface of A. argyi. The aim of this study was to elucidate the morphogenetic process and to analyze the metabolites of trichomes in A. argyi. The morphogenesis of GTs and NGTs was characterized using light, scanning, and transmission electron microscopy. The constituents of GTs were analyzed using laser microdissection combined with gas and liquid chromatography-mass spectrometry. Five developmental stages of two types of GTs and four developmental stages of one type of NGTs were observed. Two types of mature GT and one type of NGT were composed of 10, 5, and 4-6 cells, respectively. A large storage cavity was detected between the cuticle and cell walls in the first type of mature GT. Large nuclei, nucleoli, and mitochondria were observed in the basal and intermediate cells of the second type of GT. In addition, large vacuoles were observed in the basal and apical cells, and large nuclei were observed in the middle cells of NGTs. One monoterpene and seven flavonoids were identified in GTs of A. argyi. We suggest that GTs are the key tissues for the production of bioactive metabolites in A. argyi. This study provides an important theoretical basis and technical approach for clarifying the regulatory mechanisms for trichome development and bioactive metabolite biosynthesis in A. argyi.

Indexed as

ArtemisiaTrichomesFlavonoidsMorphogenesisPlant LeavesTerpenesFlavonoidsTerpenesArtemisia argyiFlavonoids and terpenoidsLaser microdissectionMorphogenesisTrichomes

Identifiers

PMID35412154
OpenAlexW4223456109

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.