Evidence map›Paper›PMID 35412098›Full record

ReviewTopics in current chemistry (Cham)2022

Development and Challenge of Fluorescent Probes for Bioimaging Applications: From Visualization to Diagnosis.

Yanchen Li, Qinhua Chen, Xiaoyan Pan, Wen Lu, Jie Zhang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Topics in current chemistry (Cham), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Emission-tunable aromatic thiadiazole derivatives based on triphenylimidazole with aggregation-induced emission activity and their application in osteosarcoma imaging.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
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  3. Biomaterials for biomarker imaging and detection.Journal of advanced research · 2026
    Review
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  18. Internalization of Pegylated Er:YACS applied nano materials · 2023
    Article
  19. Article
  20. Development and Validation of Nerve-Targeted Bacteriochlorin Sensors.Journal of the American Chemical Society · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yanchen Li *School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, 710061, China.
Qinhua Chen *Department of Pharmacy, Shenzhen Baoan Authentic TCM Therapy Hospital, Shenzhen, 518101, China.
Xiaoyan PanSchool of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, 710061, China.
Wen LuSchool of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, 710061, China. lvlu2004@xjtu.edu.cn.
Jie ZhangSchool of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, 710061, China. zhj8623@xjtu.edu.cn.ORCID http://orcid.org/0000-0003-2727-8806

Funding

National Natural Science Foundation of China 82173742Natural Science Foundation of Shaanxi Province 2020SF-240Sanming Project of Medicine in Shenzhen SZZYSM202106004
6 · The paper itself

Abstract

Fluorescent probes have been used widely in bioimaging, including biological substance detection, cell imaging, in vivo biochemical reaction process tracking, and disease biomarker monitoring, and have gradually occupied an indispensable position. Compared with traditional biological imaging technologies, such as positron emission tomography (PET) and nuclear magnetic resonance imaging (MRI), the attractive advantages of fluorescent probes, such as real-time imaging, in-depth visualization, and less damage to biological samples, have made them increasingly popular. Among them, ultraviolet-visible (UV-vis) fluorescent probes still occupy the mainstream in the field of fluorescent probes due to the advantages of available structure, simple synthesis, strong versatility, and wide application. In recent years, fluorescent probes have become an indispensable tool for bioimaging and have greatly promoted the development of diagnostics. In this review, we focus on the structure, design strategies, advantages, representative probes and latest discoveries in application fields of UV-visible fluorescent probes developed in the past 3-5 years based on several fluorophores. We look forward to future development trends of fluorescent probes from the perspective of bioimaging and diagnostics. This comprehensive review may facilitate the development of more powerful fluorescent sensors for broad and exciting applications in the future.

Indexed as

Fluorescent DyesMagnetic Resonance ImagingFluorescent DyesBioimaging applicationFluorescent probeFluorophore structureUV–vis fluorescent probe

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.