Evidence map›Paper›PMID 35412010›Full record

Trial reportClinical obesity2022

Intraclass correlation coefficients for weight loss cluster randomized trials in primary care: The PROPEL trial.

Peter T Katzmarzyk, Kara D Denstel, Corby K Martin, Robert L Newton, John W Apolzan, Emily F Mire, Ronald Horswell, William D Johnson, Andrew W Brown, Dachuan Zhang and 1 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Clinical obesity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02561221 (Promoting Successful Weight Loss in Primary Care in Louisiana), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02561221 nacompletednot on this map

Promoting Successful Weight Loss in Primary Care in Louisiana

TypeinterventionalSponsorPennington Biomedical Research CenterRan2016 to 2019Enrolled803ConditionsObesityArmsLifestyle Counseling
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Peter T KatzmarzykPennington Biomedical Research Centre, Baton Rouge, LA, USA.ORCID https://orcid.org/0000-0002-9280-6022
Kara D DenstelPennington Biomedical Research Centre, Baton Rouge, LA, USA.
Corby K MartinPennington Biomedical Research Centre, Baton Rouge, LA, USA.
Robert L NewtonPennington Biomedical Research Centre, Baton Rouge, LA, USA.
John W ApolzanPennington Biomedical Research Centre, Baton Rouge, LA, USA.
Emily F MirePennington Biomedical Research Centre, Baton Rouge, LA, USA.
Ronald HorswellPennington Biomedical Research Centre, Baton Rouge, LA, USA.
William D JohnsonPennington Biomedical Research Centre, Baton Rouge, LA, USA.
Andrew W BrownDepartment of Applied Health Science, School of Public Health-Bloomington, Indiana University, Bloomington, IN, USA.ORCID https://orcid.org/0000-0002-1758-8205
Dachuan ZhangPennington Biomedical Research Centre, Baton Rouge, LA, USA.
PROPEL Research Group

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Peter Todd Katzmarzyk · 2012 to 2026
$69.1M
Research BaseP30DK072476 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI ROBERT A KESTERSON · 2005 to 2026
$26.5M
Strengthening Causal Inference in Behavioral Obesity ResearchR25HL124208 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ALLISON, DAVID B, BROWN, ANDREW W · 2014 to 2023
$1.8M
The Mathematical Sciences in Obesity ResearchR25DK099080 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DAVID B ALLISON, Andrew W Brown · 2013 to 2026
$1.2M
NHLBI NIH HHS R25 HL124208NIDDK NIH HHS P30 DK072476NIDDK NIH HHS R25 DK099080NIGMS NIH HHS U54 GM104940NIH HHS P30DK072476NIH HHS R25DK099080NIH HHS R25HL124208NIH HHS U54 GM104940Patient-Centered Outcomes Research Institute OB-1402-10977
6 · The paper itself

Abstract

The aim of this study was to compute intra-class correlations (ICCs) for weight-related and patient-reported outcomes in a cluster randomized clinical trial (cRCT) for weight loss. Baseline and follow-up data from the Promoting Successful Weight Loss in Primary Care in Louisiana (PROPEL) cRCT were used in this analysis. ICCs were computed for baseline and follow-up measures, and changes in body weight, cardiometabolic risk factors and health-related and weight-related quality of life at 6, 12, 18 and 24 months. Baseline ICCs ranged from 0 for PROMIS measures of anxiety and fatigue to 0.055 for total cholesterol (median = 0.019). The ICCs were higher for changes and decreased over time during follow-up. The ICCs for changes were highest in the pooled sample (intervention and usual care combined) followed by the intervention and usual care groups, respectively. The results demonstrated significant ICCs for several outcomes in a weight loss cRCT. The ICCs differed in magnitude depending on whether baseline versus longitudinal data were used, whether data were combined across treatment arms or were considered separately, and varied across the follow-up period. All these factors must be considered when choosing an ICC to inform sample size estimates for future weight loss cRCTs conducted in primary care settings.

Indexed as

Quality of LifeWeight LossCluster AnalysisHumansPrimary Health Caredesign effectgroup-randomizedobesitypowersample size

Identifiers

PMID35412010
PMCPMC9283264

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.