Evidence map›Paper›PMID 35411995›Full record

ArticleHuman brain mapping2022

Altered myelination in youth born with congenital heart disease.

Kaitlyn Easson, Guillaume Gilbert, Charles V Rohlicek, Christine Saint-Martin, Maxime Descoteaux, Sean C L Deoni, Marie Brossard-Racine

Open access · goldAbstract read
In one paragraph

Article in Human brain mapping, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Kaitlyn EassonAdvances in Brain & Child Development (ABCD) Research Laboratory, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.
Guillaume GilbertMR Clinical Science, Philips Healthcare, Mississauga, Ontario, Canada.
Charles V RohlicekDepartment of Pediatrics, Division of Cardiology, Montreal Children's Hospital, Montreal, Quebec, Canada.
Christine Saint-MartinDepartment of Medical Imaging, Division of Pediatric Radiology, Montreal Children's Hospital, Montreal, Quebec, Canada.
Maxime DescoteauxSherbrooke Connectivity Imaging Laboratory (SCIL), Université de Sherbrooke, Sherbrooke, Quebec, Canada.
Sean C L DeoniAdvanced Baby Imaging Lab, Brown University, Providence, Rhode Island, USA.
Marie Brossard-RacineAdvances in Brain & Child Development (ABCD) Research Laboratory, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.ORCID 0000-0003-0641-0054
Montreal Children's Hospital · CABrown University · USMcGill University Health Centre · CAPhilips (Finland) · FIUniversité de Sherbrooke · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brain injury and dysmaturation is common in fetuses and neonates with congenital heart disease (CHD) and is hypothesized to result in persistent myelination deficits. This study aimed to quantify and compare myelin content in vivo between youth born with CHD and healthy controls. Youth aged 16 to 24 years born with CHD and healthy age- and sex-matched controls underwent brain magnetic resonance imaging including multicomponent driven equilibrium single pulse observation of T

Indexed as

Heart Defects, CongenitalWhite MatterAdolescentBrainHumansInfant, NewbornMagnetic Resonance ImagingMyelin Sheathcongenital heart diseasemyelinationneurodevelopmentquantitative magnetic resonance imaging

Identifiers

PMID35411995
PMCPMC9248320
OpenAlexW4223416713

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.