Evidence map›Paper›PMID 35411972›Full record

ArticleSkin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)2022

Efficacy of a fine fiber film applied with a water-based lotion to improve dry skin.

Yu Gabe, Masayuki Uchiyama, Shun Sasaoka, Naomi Amari, Asuka Imai, Akira Hachiya, Akira Kiyomine

Open access · hybridAbstract read
In one paragraph

Article in Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Development of a biomarker-based platform for comprehensive skin characterization using minimally invasive skin sampling and quantitative real-time PCR.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
  3. Microneedles: A novel clinical technology for evaluating skin characteristics.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
  4. Efficacy of a fine fiber film applied with a water-based lotion to improve dry skin.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2022
    Article
  5. Biological Effects of a Fine Fiber Film Treated With a Lotion to Improve Dry Skin.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Yu GabeBiological Science Research, Kao Corporation, Odawara, Japan.ORCID https://orcid.org/0000-0003-0081-2511
Masayuki UchiyamaSkin Care Products Research, Kao Corporation, Sumida, Japan.
Shun SasaokaAnalytical Science Research, Kao Corporation, Sumida, Japan.
Naomi AmariProcessing Development Research, Kao Corporation, Haga, Japan.
Asuka ImaiKao R&D, Kao USA Inc., Cincinnati, Ohio, USA.ORCID https://orcid.org/0000-0001-7927-5709
Akira HachiyaPlanning and Implementation, Kao Corporation, Sumida, Japan.
Akira KiyomineKao R&D, Kao USA Inc., Cincinnati, Ohio, USA.
Kao Corporation (Japan) · JPKao Corporation (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDry skin can trigger eczema that affects >10% of the US population. Dressing films have been developed to improve diseased skin, but there is limited knowledge about their effects, especially for dry skin-related symptoms. We developed an electrospinning method that creates a coating film, called a fine fiber (FF) film, characterized by the production of a transparent, thin, flexible, and adherent membrane on the skin surface.

objectiveThe aim of this pilot study was to examine the effects of the FF film on dry skin.

methodsThree treatments (lotion only, lotion with the FF film, and lotion with an alternative film) were designed to treat subjects with rough skin on their lower legs. Twenty-four females were enrolled and used either a water-based lotion U or a petrolatum-based lotion P and the FF film for 2 weeks followed by a regression phase for 1 week. Skin hydration and roughness scores were assessed as were the subjects' perceptions of the effects.

resultsWhen the FF film was applied with lotion U, skin hydration was significantly improved even after 1 week, accompanied by a significant improvement of skin roughness and an increase in skin hydration by the end of the regression phase. An evaluation of moisture permeability suggested that the FF film, especially with lotion U, performed as a semipermeable membrane with optimal moisture healing effects on dry skin.

conclusionThe FF film together with a water-based lotion is a promising treatment to quickly improve dry skin conditions.

Indexed as

Skin DiseasesWaterDouble-Blind MethodEmollientsFemaleHumansPilot ProjectsSkinSkin CreamTreatment OutcomeEmollientsWaterconductancedirect-electrospinning (D-ES)dry skinfine fiber (FF)hydration

Identifiers

PMID35411972
PMCPMC9907623
OpenAlexW4223526652

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.