Evidence map›Paper›PMID 35411488›Full record

ArticleMolecular genetics and genomics : MGG2022

A new linear combination method of haplogroup distribution central vectors to model population admixtures.

Tibor Török, Kitti Maár, István Gergely Varga, Zoltán Juhász

Open access · hybridAbstract read
In one paragraph

Article in Molecular genetics and genomics : MGG, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Tibor TörökDepartment of Genetics, University of Szeged, Szeged, Hungary.
Kitti MaárDepartment of Genetics, University of Szeged, Szeged, Hungary.
István Gergely VargaDepartment of Archaeogenetics, Institute of Hungarian Research, Budapest, Hungary.
Zoltán JuhászInstitute of Technical Physics and Materials Science, Centre for Energy Research, Budapest, Hungary. juhasz@mfa.kfki.hu.ORCID http://orcid.org/0000-0002-0200-7033
University of Szeged · HUInstitute for Technical Physics and Materials Science · HU

Funding

Pallas Athéné Domus Scientiae Alapítvány 122/2019
6 · The paper itself

Abstract

We introduce a novel population genetic approach suitable to model the origin and relationships of populations, using new computation methods analyzing Hg frequency distributions. Hgs were selected into groups which show correlated frequencies in subsets of populations, based on the assumption that correlations were established in ancient separation, migration and admixture processes. Populations are defined with this universal Hg database, then using unsupervised artificial intelligence, central vectors (CVs) are determined from local condensations of the Hg-distribution vectors in the multidimensional point system. Populations are clustered according to their proximity to CVs. We show that CVs can be regarded as approximations of ancient populations and real populations can be modeled as weighted linear combinations of the CVs using a new linear combination algorithm based on a gradient search for the weights. The efficacy of the method is demonstrated by comparing Copper Age populations of the Carpathian Basin to Middle Age ones and modern Hungarians. Our analysis reveals significant population continuity since the Middle Ages, and the presence of a substrate component since the Copper Age.

Indexed as

Artificial IntelligenceMercuryAlgorithmsDNA, MitochondrialGenetics, PopulationHaplotypesHungaryPhylogenyDNA, MitochondrialMercuryArchaeogeneticsArtificial intelligenceHaplogroupsSelf learning

Identifiers

PMID35411488
PMCPMC9130205
OpenAlexW4223499713

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.