Evidence map›Paper›PMID 35411433›Full record

ReviewAbdominal radiology (New York)2022

Gastric neuroendocrine neoplasms: a primer for radiologists.

Molly E Roseland, Isaac R Francis, Kimberly L Shampain, Erica B Stein, Ashish P Wasnik, John D Millet

Abstract readReview
PubMed Publisher
In one paragraph

Review in Abdominal radiology (New York), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Molly E RoselandDepartment of Radiology, Michigan Medicine, University of Michigan, 1500 East Medical Center Drive, B1D502, Ann Arbor, MI, 48109, USA. mollyroselandmd@gmail.com.ORCID 0000-0002-5885-1487
Isaac R FrancisDepartment of Radiology, Michigan Medicine, University of Michigan, 1500 East Medical Center Drive, B1D502, Ann Arbor, MI, 48109, USA.
Kimberly L ShampainDepartment of Radiology, Michigan Medicine, University of Michigan, 1500 East Medical Center Drive, B1D502, Ann Arbor, MI, 48109, USA.ORCID 0000-0002-6094-1676
Erica B SteinDepartment of Radiology, Michigan Medicine, University of Michigan, 1500 East Medical Center Drive, B1D502, Ann Arbor, MI, 48109, USA.ORCID 0000-0002-7339-8107
Ashish P WasnikDepartment of Radiology, Michigan Medicine, University of Michigan, 1500 East Medical Center Drive, B1D502, Ann Arbor, MI, 48109, USA.ORCID 0000-0002-4823-8929
John D MilletDepartment of Radiology, Michigan Medicine, University of Michigan, 1500 East Medical Center Drive, B1D502, Ann Arbor, MI, 48109, USA.ORCID 0000-0002-6703-8818
Michigan Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric neuroendocrine neoplasms are uncommon tumors with variable differentiation and malignant potential. Three main subtypes are recognized: type 1, related to autoimmune atrophic gastritis; type 2, associated with Zollinger-Ellison and MEN1 syndrome; and type 3, sporadic. Although endoscopy alone is often sufficient for diagnosis and management of small, indolent, multifocal type 1 tumors, imaging is essential for evaluation of larger, high-grade, and type 2 and 3 neoplasms. Hypervascular intraluminal gastric masses are typically seen on CT/MRI, with associated perigastric lymphadenopathy and liver metastases in advanced cases. Somatostatin receptor nuclear imaging (such as Ga-68-DOTATATE PET/CT) may also be used for staging and assessing candidacy for peptide receptor radionuclide therapy. Radiotracer uptake is more likely in well-differentiated, lower-grade tumors, and less likely in poorly differentiated tumors, for which F-18-FDG-PET/CT may have additional value. Understanding disease pathophysiology and evolving histologic classifications is particularly useful for radiologists, as these influence tumor behavior, preferred imaging, therapy options, and patient prognosis.

Indexed as

Neuroendocrine TumorsOrganometallic CompoundsStomach NeoplasmsGallium RadioisotopesHumansPositron-Emission TomographyPositron Emission Tomography Computed TomographyRadiologistsRadionuclide Imagingcopper dotatate CU-64Gallium-68Gallium RadioisotopesOrganometallic CompoundsAutoimmune atrophic gastritisComputed tomography (CT)Gastric carcinoidGastric neuroendocrine neoplasmMagnetic resonance imaging (MRI)Somatostatin receptor imagingZollinger–Ellison syndrome

Identifiers

PMID35411433
OpenAlexW4223558156

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.