Evidence map›Paper›PMID 35411353›Full record

ArticleBiomaterials science2022

Hyaluronan and elastin-like protein (HELP) gels significantly improve microsphere retention in the myocardium.

Riley A Suhar, Vanessa M Doulames, Yueming Liu, Meghan E Hefferon, Oscar Figueroa, Hana Buabbas, Sarah C Heilshorn

Open access · greenAbstract read
In one paragraph

Article in Biomaterials science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Submucosal Hydrogel for Spring-Mediated Intestinal Lengthening.Journal of biomedical materials research. Part A · 2025
    Article
  2. Review
  3. Engineered Hydrogels for Organoid Models of Human Nonalcoholic Fatty Liver Disease.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  4. Engineered Protein Hydrogels as Biomimetic Cellular Scaffolds.Advanced materials (Deerfield Beach, Fla.) · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Riley A SuharDepartment of Materials Science and Engineering, Stanford University, Stanford, California 94305, USA. heilshorn@stanford.edu.ORCID http://orcid.org/0000-0003-4220-8320
Vanessa M DoulamesDepartment of Materials Science and Engineering, Stanford University, Stanford, California 94305, USA. heilshorn@stanford.edu.
Yueming LiuDepartment of Materials Science and Engineering, Stanford University, Stanford, California 94305, USA. heilshorn@stanford.edu.
Meghan E HefferonDepartment of Materials Science and Engineering, Stanford University, Stanford, California 94305, USA. heilshorn@stanford.edu.ORCID http://orcid.org/0000-0002-6685-2121
Oscar FigueroaEllicott City, Maryland 21043, USA. ozzief@alum.mit.edu.
Hana BuabbasDepartment of Materials Science and Engineering, Stanford University, Stanford, California 94305, USA. heilshorn@stanford.edu.
Sarah C HeilshornDepartment of Materials Science and Engineering, Stanford University, Stanford, California 94305, USA. heilshorn@stanford.edu.ORCID http://orcid.org/0000-0002-9801-6304
Stanford University · US

Funding

Graduate Training Program in BiotechnologyT32GM008412 · NIGMS · STANFORD UNIVERSITY · PI COCHRAN, JENNIFER R · 1991 to 2020
$5.5M
Injectable Hydrogels to Deliver Gene Therapy for Myocardial InfarctR01HL151997 · NHLBI · STANFORD UNIVERSITY · PI HEILSHORN, SARAH C · 2020 to 2023
$1.7M
Injectable Hydrogels to Protect Transplanted Cells from HypoxiaR01EB027666 · NIBIB · STANFORD UNIVERSITY · PI HEILSHORN, SARAH C, PLANT, GILES · 2019 to 2022
$1.4M
Engineered biomaterials to modulate cell-cell signaling for the robust expansion of stem cellsR01EB027171 · NIBIB · STANFORD UNIVERSITY · PI HEILSHORN, SARAH C · 2019 to 2022
$1.4M
Engineered Protein Hydrogels to Modulate Adipose-derived Stromal Cell Secretome and Exosomes for Injectable Myocardial Infarction TherapyR21HL138042 · NHLBI · STANFORD UNIVERSITY · PI HEILSHORN, SARAH C · 2017 to 2018
$435k
NHLBI NIH HHS R01 HL151997NHLBI NIH HHS R21 HL138042NIBIB NIH HHS R01 EB027171NIBIB NIH HHS R01 EB027666NIGMS NIH HHS T32 GM008412
6 · The paper itself

Abstract

Heart disease is the leading cause of death globally, and delivery of therapeutic cargo (

Indexed as

ElastinHyaluronic AcidAnimalsHydrogelsMicrospheresMyocardiumRatsElastinHyaluronic AcidHydrogels

Identifiers

PMID35411353
PMCPMC9123900
OpenAlexW4223564059

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.