ArticleClinical interventions in aging2022
Nomogram for Persistent Post-Stroke Depression and Decision Curve Analysis.
Article in Clinical interventions in aging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.
- Accuracy of Machine Learning in Predicting Post-Stroke Depression: A Systematic Review and Meta-Analysis.Brain and behavior · 2025Pooled it
- Non-Invasive Brain Stimulation Progression in Post-Stroke Depression Treatment: A Systematic Review.Alpha psychiatry · 2024Pooled it
- A m6A/m1A/m5C-related eight-gene signature predicts prognosis and correlates with immune microenvironment in pediatric acute myeloid leukemia.Translational pediatrics · 2026Article
- Association BetweenNeuropsychiatric disease and treatment · 2026Article
- Establishment and validation of a model for predicting depression risk in stroke patients.BMC psychiatry · 2025Article
- Network-based predictive models for artificial intelligence: an interpretable application of machine learning techniques in the assessment of depression in stroke patients.BMC geriatrics · 2025Article
- Construction and Validation of a Major Depression Risk Predictive Model for Patients with Coronary Heart Disease: Insights from NHANES 2005-2018.Reviews in cardiovascular medicine · 2025Article
- Dynamic Nomogram for Predicting the Fall Risk of Stroke Patients: An Observational Study.Clinical interventions in aging · 2025Observational
- Liver function test indices-based prediction model for post-stroke depression: a multicenter, retrospective study.BMC medical informatics and decision making · 2023Article
- Development and validation of a nomogram model for predicting unfavorable functional outcomes in ischemic stroke patients after acute phase.Frontiers in aging neuroscience · 2023Article
- What should nurses do on post-stroke depression? A global systematic assessment of clinical practice guidelines.BMJ open · 2022Article
- The enigma of vascular depression in old age: a critical update.Journal of neural transmission (Vienna, Austria : 1996) · 2022Review
- A new nomogram including total cerebral small vessel disease burden for individualized prediction of early-onset depression in patients with acute ischemic stroke.Frontiers in aging neuroscience · 2022Article
- Prognostic Value of an Integrated Coagulation Score in Ischemic Stroke After Endovascular Therapy: A retrospective case series.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Previous studies have shown that persistent post-stroke depression (PSD) was associated with unfavorable prognosis. The aim of this multicenter prospective study was to investigate the predictors associated with persistent PSD, develop a nomogram and validate its clinical usefulness by decision curve analysis (DCA). Patients and Methods: A total of 875 acute ischemic stroke patients from four hospitals were consecutively recruited and completed 1-year follow-ups. Sociodemographic indicators, vascular risk factors, clinical information, serum biochemical indicators and cytokines were collected on admission. The functional outcome was assessed at 1 year after stroke. Persistent depression was defined as having a presentation of depression at each follow-up points and the depressive symptoms occurring persistently since the diagnosis of depression. Results: There were 513 patients who experienced PSD during the 1-year follow-up, the cumulative incidence of PSD within 1 year was 58.6%. Persistent PSD was recorded in 289 patients, of which 59 (20.4%) result in unfavorable outcomes. The risk factors of persistent PSD in 1 year after stroke were the Hamilton Depression Scale-17 items (HAMD-17) score at admission, serum direct bilirubin and free serum thyroxine (FT4) level and activated partial thromboplastin time (APTT). Nomogram conducted based on these factors has a C-index (± standard deviation) of 0.655 ± 0.039, and the DCA demonstrated that the nomogram had a favorable clinical utility. Conclusion: We found that persistent depression after stroke in the first-year time course after stroke was associated with HAMD-17 score at admission, lower serum direct bilirubin and FT4 level, and APTT. A nomogram was developed with advisable clinical usefulness in our study.
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