ArticleScientific reports2022
An in vivo model for overloading-induced soft tissue injury.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Plantar Tissue Characteristics in People With Diabetes With and Without Peripheral Neuropathy: A Novel Explanatory Model for DPN Risk Assessment.Journal of diabetes · 2025Article
- Understanding occipital pressure sores in UK military casualties: a pilot study in healthy military personnel.BMJ military health · 2024Article
- The Importance of Preconditioning for the Sonographic Assessment of Plantar Fascia Thickness and Shear Wave Velocity.Sensors (Basel, Switzerland) · 2024Article
- Reliability and Validity of Shore Hardness in Plantar Soft Tissue Biomechanics.Sensors (Basel, Switzerland) · 2024Article
- Predicting the diabetic foot in the population of type 2 diabetes mellitus from tongue images and clinical information using multi-modal deep learning.Frontiers in physiology · 2024Article
- Effect of Vacuum Sealing Drainage on Soft Tissue Injury of Traumatic Fracture and Its Effect on Wound Recovery.Evidence-based complementary and alternative medicine : eCAM · 2022Article
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Authors and funding
2 authors.
Funding
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Abstract
This proof-of-concept study demonstrates that repetitive loading to the pain threshold can safely recreate overloading-induced soft tissue damage and that localised tissue stiffening can be a potential marker for injury. This concept was demonstrated here for the soft tissue of the sole of the foot where it was found that repeated loading to the pain threshold led to long-lasting statistically significant stiffening in the overloaded areas. Loading at lower magnitudes did not have the same effect. This method can shed new light on the aetiology of overloading injury in the foot to improve the management of conditions such as diabetic foot ulceration and heel pain syndrome. Moreover, the link between overloading and tissue stiffening, which was demonstrated here for the first time for the plantar soft tissue, opens the way for an assessment of overloading thresholds that is not based on the subjective measurement of pain thresholds.
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