ArticleThorax2022
Tracking of lung function from 10 to 35 years after being born extremely preterm or with extremely low birth weight.
Article in Thorax, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
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Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.
- Impaired lung function and associated risk factors in children born prematurely: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2024Pooled it
- Mesenchyme-derived inflammation during the saccular stage recruits macrophages and alters lung development.JCI insight · 2026Article
- Maternal and perinatal nutritional programming of lung health and disease in childhood and early adulthood: Research gaps and opportunities-National Heart, Lung, and Blood Institute/National Institutes of Health Workshop Report.The Journal of allergy and clinical immunology · 2026Article
- Does neonatal sepsis affect the lung function of children and adults born prematurely?Pediatric research · 2026Article
- Treatable traits of small airway dysfunction in children with asthma and advances in small airway-targeted therapeutic research: a narrative review.Translational pediatrics · 2026Review
- Long-term pulmonary outcomes in BPD throughout the life-course.Journal of perinatology : official journal of the California Perinatal Association · 2026Review
- Lung function in adults born with very low birth weight from young to mid-adulthood.Pediatric research · 2026Article
- A study on differences in lung function development and longitudinal patterns between preterm infants of different gestational ages and term infants.Frontiers in pediatrics · 2026Article
- Quantitative proteomics links mitochondrial dysfunction to metabolic changes and epithelial differentiation defects in hyperoxia-exposed neonatal airway cells.American journal of physiology. Lung cellular and molecular physiology · 2026Article
- Respiratory Sequelae of Prematurity in School-Age Children: Is Bronchopulmonary Dysplasia Still the Primary Risk Factor?Children (Basel, Switzerland) · 2025Article
- Dynamics of postnatal upper airway bacteria colonization in preterm infants <1000g and bronchopulmonary dysplasia.Scientific reports · 2025Article
- Comparison of nSOFA and RSS for predicting bronchopulmonary dysplasia in preterm infants: a retrospective cohort study.BMJ paediatrics open · 2025Article
- Defining endotypes of bronchopulmonary dysplasia in preterm infants to improve precision-based therapies.JCI insight · 2025Review
- Lung MRI scoring reveals persistence of emphysema-like changes in lungs of infants born preterm at (pre)school age.ERJ open research · 2025Article
- The Reference Interval for the Attainment of Comparable Term Functional Levels of Pulmonary Oxygenation Capacity in Healthy Preterm Infants: A Single-Center Retrospective Study.Pediatric pulmonology · 2025Article
- Nocturnal pulse oxygen saturation dynamics at simulated high altitude: Predictive value for acute mountain sickness in healthy men born pre-term.Experimental physiology · 2025Article
- Perinatal Antibiotic Exposure and Respiratory Outcomes in Children Born Preterm.JAMA network open · 2025Article
- Lung function outcomes in adults born extremely preterm across three decades of advancing perinatal medicine.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Outpatient Respiratory Outcomes in Extremely Preterm Children During the First 3 Years of Life.Pediatric pulmonology · 2025Article
- Clinical Characteristics of Chronic Obstructive Pulmonary Disease according to Smoking Status.Tuberculosis and respiratory diseases · 2025Article
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLifelong pulmonary consequences of being born extremely preterm or with extremely low birth weight remain unknown. We aimed to describe lung function trajectories from 10 to 35 years of age for individuals born extremely preterm, and address potential cohort effects over a period that encompassed major changes in perinatal care.
methodsWe performed repeated spirometry in three population-based cohorts born at gestational age ≤28 weeks or with birth weight ≤1000 g during 1982-85, 1991-92 and 1999-2000, referred to as extremely preterm-born, and in term-born controls matched for age and gender. Examinations were performed at 10, 18, 25 and 35 years. Longitudinal data were analysed using mixed models regression, with the extremely preterm-born stratified by bronchopulmonary dysplasia (BPD).
resultsWe recruited 148/174 (85%) eligible extremely preterm-born and 138 term-born. Compared with term-born, the extremely preterm-born had lower z-scores for forced expiratory volume in 1 s (FEV
conclusionsLung function after extremely preterm birth tracked in parallel, but significantly below the trajectories of term-born from 10 to 35 years, including the incipient age-related decline from 25 to 35 years. The deficits versus term-born decreased with each decade of birth from 1980 to 2000.
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