Evidence map›Paper›PMID 35410931›Full record

ArticleBMJ open2022

Implementing a choice of pulmonary rehabilitation models in chronic obstructive pulmonary disease (HomeBase2 trial): protocol for a cluster randomised controlled trial.

Anne E Holland, Arwel W Jones, Ajay Mahal, Natasha A Lannin, Narelle Cox, Graham Hepworth, Paul O'Halloran, Christine F McDonald

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04217330 (HomeBase2), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04217330 naactive not recruitingnot on this map

HomeBase2: An Implementation Trial to Improve Access to Pulmonary Rehabilitation in People With Chronic Obstructive Pulmonary Disease

TypeinterventionalSponsorMonash UniversityRan2021 to 2026Enrolled490ConditionsChronic Obstructive Pulmonary DiseaseArmsChoice of home-based or centre-based pulmonary rehabilitation, Centre-based pulmonary rehabilitation
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anne E HollandRespiratory Research@Alfred, Central Clinical School, Monash University, Melbourne, Victoria, Australia a.holland@alfred.org.au.ORCID 0000-0003-2061-845X
Arwel W JonesRespiratory Research@Alfred, Central Clinical School, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0003-1689-8065
Ajay MahalThe Nossal Global Institute for Global Health, University of Melbourne, Melbourne, Victoria, Australia.
Natasha A LanninDepartment of Clinical Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0002-2066-8345
Narelle CoxRespiratory Research@Alfred, Central Clinical School, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0002-6977-1028
Graham HepworthStatistical Consulting Centre, The University of Melbourne, Melbourne, Victoria, Australia.
Paul O'HalloranDepartment of Public Health, La Trobe University, Bundoora, Victoria, Australia.
Christine F McDonaldDepartment of Respiratory and Sleep Medicine, Austin Health, Heidelberg, Victoria, Australia.ORCID 0000-0001-6481-3391

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThere is compelling evidence that either centre-based or home-based pulmonary rehabilitation improves clinical outcomes in chronic obstructive pulmonary disease (COPD). There are known health service and personal barriers which prevent potentially eligible patients from accessing the benefits of pulmonary rehabilitation. The aim of this hybrid effectiveness-implementation trial is to examine the effects of offering patients a choice of pulmonary rehabilitation locations (home or centre) compared with offering only the traditional centre-based model. METHOD AND ANALYSIS: This is a two-arm cluster randomised, controlled, assessor-blinded trial of 14 centre-based pulmonary rehabilitation services allocated to intervention (offering choice of home-based or centre-based pulmonary rehabilitation) or control (continuing to offer centre-based pulmonary rehabilitation only), stratified by centre-based programme setting (hospital vs non-hospital). 490 participants with COPD will be recruited. Centre-based pulmonary rehabilitation will be delivered according to best practice guidelines including supervised exercise training for 8 weeks. At intervention sites, the home-based pulmonary rehabilitation will be delivered according to an established 8-week model, comprising of one home visit, unsupervised exercise training and telephone calls that build motivation for exercise participation and facilitate self-management. The primary outcome is all-cause, unplanned hospitalisations in the 12 months following rehabilitation. Secondary outcomes include programme completion rates and measurements of 6-minute walk distance, chronic respiratory questionnaire, EQ-5D-5L, dyspnoea-12, physical activity and sedentary time at the end of rehabilitation and 12 months following rehabilitation.Direct healthcare costs, indirect costs and changes in EQ-5D-5L will be used to evaluate cost-effectiveness. A process evaluation will be undertaken to understand how the choice model is implemented and explore sustainability beyond the clinical trial. ETHICS AND DISSEMINATION: Alfred Hospital Ethics Committee has approved this protocol. The trial findings will be published in peer-reviewed journals, submitted for presentation at conferences and disseminated to patients across Australia with support from national lung charities and societies. TRIAL REGISTRATION NUMBER: NCT04217330.

Indexed as

Pulmonary Disease, Chronic ObstructiveQuality of LifeCost-Benefit AnalysisDyspneaHumansRandomized Controlled Trials as TopicRehabilitation CentersChronic airways diseaseEmphysemaREHABILITATION MEDICINE

Identifiers

PMID35410931
PMCPMC9003613

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.