Evidence map›Paper›PMID 35410926›Full record

Observational studyBMJ open2022

Prevalence, symptom burden and under-diagnosis of chronic obstructive pulmonary disease in Polish lung cancer screening population: a cohort observational study.

Aleksandra Undrunas, Piotr Kasprzyk, Aleksandra Rajca, Krzysztof Kuziemski, Witold Rzyman, Tomasz Zdrojewski

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Aleksandra UndrunasDepartment of Allergology and Pneumonology, Medical University of Gdansk, Gdansk, Poland a.undrunas@gumed.edu.pl.ORCID 0000-0003-3874-3531
Piotr KasprzykDepartment of Preventive Medicine and Education, Medical University of Gdansk, Gdansk, Poland.
Aleksandra RajcaDepartment of Preventive Medicine and Education, Medical University of Gdansk, Gdansk, Poland.
Krzysztof KuziemskiDepartment of Allergology and Pneumonology, Medical University of Gdansk, Gdansk, Poland.
Witold RzymanThoracic Surgery, Medical University of Gdansk, Gdansk, Poland.
Tomasz ZdrojewskiDepartment of Preventive Medicine and Education, Medical University of Gdansk, Gdansk, Poland.ORCID 0000-0001-6015-8561
Gdańsk Medical University · PLThoracic Surgery Foundation · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesLung cancer screening using low-dose CT may be not effective without considering the presence of comorbidities related to chronic smoking. The aim of the study was to establish the prevalence of chronic obstructive pulmonary disease (COPD) in group of phighlight the potential benefits atients participating in the largest Polish lung cancer screening programme MOLTEST-BIS and attempt to confirm the necessity of combined lung cancer and COPD screening.

designCohort, prospective study.

settingMedical University of Gdańsk, Poland

participantsThe study included 754 participants in lung cancer screening trial from the Pomeranian region, aged 50-70 years old, current and former smokers with a smoking history ≥30 pack-years. PRIMARY AND SECONDARY OUTCOME MEASURES: Questionnaire, physical examination, anthropometric measurements, spirometry test before and after inhaled bronchodilator (400 µg of salbutamol)

resultsObstructive disorders were diagnosed in 186 cases (103 male and 83 female). In the case of 144 participants (19.73%), COPD was diagnosed. Only 13.3% of participants with COPD were known about the disease earlier. According to classification of airflow limitation 55.6% of diagnosed COPD were in Global Initiative for Chronic Obstructive Lung Disease (GOLD) 1 (mild), 38.9% in GOLD 2 (moderate), 4.9% in GOLD 3 (severe) and 0.7% in GOLD 4 (very severe) stage. Women with recognition of COPD were younger than men (63.7 vs 66.3 age) and they smoked less cigarettes (41.1 vs 51.9 pack-years).

conclusionsPrevalence of COPD in Polish lung cancer screening cohort is significant. The COPD in this group is remarkably under-diagnosed. Most diagnosed COPD cases were in the initial stage of advancement. This early detection of airflow limitation highlights the potential benefits arising from combined oncological-pulmonary screening.NKBBN.

Indexed as

Lung NeoplasmsPulmonary Disease, Chronic ObstructiveAgedEarly Detection of CancerFemaleForced Expiratory VolumeHumansMaleMiddle AgedPolandPrevalenceProspective StudiesRisk FactorsSpirometrycardiothoracic surgerychronic airways diseasediagnostic radiologyoncologyrespiratory tract tumoursthoracic medicine

Identifiers

PMID35410926
PMCPMC9003611
OpenAlexW4223460261

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.