Evidence map›Paper›PMID 35410326›Full record

Trial reportBMC public health2022

Substance use is associated with condomless anal intercourse among men who have sex with men in India: a partner-level analysis.

Sandeep Prabhu, Shruti H Mehta, Allison M McFall, Aylur K Srikrishnan, Canjeevaram K Vasudevan, Gregory M Lucas, David D Celentano, Sunil S Solomon

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01686750 (A Cluster Randomized Trial of Integrated Care Centers to Improve Access to HIV Prevention, Testing, and Treatment Services Among High-Risk Vulnerable Populations in India), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01686750 nacompletednot on this map

A Cluster Randomized Trial of Integrated Care Centers to Improve Access to HIV Prevention, Testing, and Treatment Services Among High-Risk Vulnerable Populations in India

TypeinterventionalSponsorJohns Hopkins UniversityRan2012 to 2017Enrolled21,726ConditionsHIV InfectionArmsIntegrated care centers
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. An online study to understand chemsex in India.Indian journal of psychiatry · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Sandeep PrabhuJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. sandeepp@uw.edu.
Shruti H MehtaJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Allison M McFallJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Aylur K SrikrishnanY.R. Gaitonde Centre for AIDS Research and Education, Chennai, India.
Canjeevaram K VasudevanY.R. Gaitonde Centre for AIDS Research and Education, Chennai, India.
Gregory M LucasJohns Hopkins University School of Medicine, 1830 E Monument St, Rm 444, Baltimore, MDMaryland, 21287, USA.
David D CelentanoJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Sunil S SolomonJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. sss@jhmi.edu.
Johns Hopkins University · USYR Gaitonde Centre for AIDS Research and Education · INUniversity of Washington · US

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Richard E. Chaisson · 2012 to 2026
$67.0M
Strategies to improve the HIV care continuum among key populations in IndiaR01DA041034 · NIDA · JOHNS HOPKINS UNIVERSITY · PI LUCAS, GREGORY M, MEHTA, SHRUTI H · 2015 to 2021
$6.7M
Preventing HIV Infection Among MSM in Southern IndiaR01MH089266 · NIMH · JOHNS HOPKINS UNIVERSITY · PI CELENTANO, DAVID D. · 2010 to 2015
$2.9M
Treatment outcomes and comorbidity in HIV-infected IDUK24DA035684 · NIDA · JOHNS HOPKINS UNIVERSITY · PI LUCAS, GREGORY M · 2014 to 2024
$1.5M
NIAID NIH HHS P30 AI094189NIDA NIH HHS K24 DA035684NIDA NIH HHS R01 DA041034NIMH NIH HHS R01 MH089266
6 · The paper itself

Abstract

backgroundMen who have sex with men (MSM) bear a disproportionately high burden of new HIV infections while lagging behind other populations with respect to engagement across the HIV care continuum. General risk factors for condomless anal intercourse (CAI) among MSM are well studied but there is a paucity of partner-level data, where emerging evidence suggests that much of the variation in condom use occurs.

methodsMSM were recruited across 10 cities in India using respondent-driven sampling (RDS) from 2016-17. Among the individuals who reported sexual intercourse in the prior 6 months, condom use and partner characteristics of the last 4 partners were captured. Correlates of CAI at the individual and partner level were determined using Poisson regression models using generalized estimating equations and incorporating RDS-II weights, which weights estimates for the participant's network size.

resultsAmong the 8,086 individuals, 21,723 sexual partnerships were analyzed. The prevalence of CAI was 46.9% and most partners were casual or one-time (70.7%) with partner HIV status reported as unknown in 42.6% of the sexual encounters. In multivariable analyses, partner-level characteristics associated with higher likelihood of CAI included unknown partner HIV status (aPR vs. known HIV negative partner: 1.34; 95% confidence interval (CI): 1.27-1.43) and use of alcohol/ drugs prior to intercourse either sometimes (aPR 1.42; 95% CI: 1.33-1.51) or always (aPR 1.31; 95% CI: 1.23-1.41). At an individual level, any HIV treatment literacy was associated with a lower likelihood of CAI (aPR 0.80; 95% CI: 0.74-0.86).

conclusionsTo reduce HIV transmission among this population of MSM across India, combination interventions are likely needed. Interventions targeting substance use and education as well as initiatives to increase self-testing are urgently needed among MSM in India and have the potential to reduce HIV transmission in this high-risk population. Trial registration ClinicalTrials.gov Identifier: NCT01686750. Date of Registration: September 18, 2012.

Indexed as

HIV InfectionsSexual and Gender MinoritiesSubstance-Related DisordersCoitusCondomsCross-Sectional StudiesHomosexuality, MaleHumansIndiaMaleSexual BehaviorSexual PartnersAIDSCondomless anal intercourseHIVIndiaMSM

Identifiers

PMID35410326
PMCPMC9004170
OpenAlexW4223423007

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.