Evidence map›Paper›PMID 35410183›Full record

ArticleBMC nephrology2022

Associations between physical activity levels and renal recovery following acute kidney injury stage 3: a feasibility study.

Anam Asad, Amal Thomas, Maurice Dungey, Katherine L Hull, Daniel S March, James O Burton

Open access · goldAbstract read
In one paragraph

Article in BMC nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Anam AsadDepartment of Cardiovascular Sciences, University of Leicester, Leicester, UK.
Amal ThomasDepartment of Cardiovascular Sciences, University of Leicester, Leicester, UK.
Maurice DungeyDepartment of Cardiovascular Sciences, University of Leicester, Leicester, UK.
Katherine L HullDepartment of Cardiovascular Sciences, University of Leicester, Leicester, UK.
Daniel S MarchDepartment of Cardiovascular Sciences, University of Leicester, Leicester, UK.
James O BurtonDepartment of Cardiovascular Sciences, University of Leicester, Leicester, UK. jb343@le.ac.uk.
University of Leicester · GBLeicester General Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute kidney injury (AKI) can lead to chronic kidney disease, which results in poor long-term outcomes. There is plausibility that increased levels of physical activity may promote renal recovery post-AKI. This study aimed to investigate associations between physical activity levels and renal recovery following stage 3 AKI, and to assess the feasibility of measuring physical activity levels in this population.

methodsForty One hospitalised patients with AKI stage 3 were enrolled. Serum creatinine and estimated glomerular filtration rate (eGFR) were collected at 12 months prior to the development of AKI, during the hospital admission when the episode of AKI stage 3 occurred, and at 1-, 3- and 6-months post discharge. All participants completed the General Practice Activity Questionnaire (GPPAQ) to assess physical activity levels. A pedometer was also worn for 7 days immediately following discharge and at 6-months post discharge to ascertain an average daily step count. Feasibility outcomes including eligibility, recruitment and retention rates, and losses to follow up were also assessed.

resultsThe average (± SD) baseline eGFR and median (IQR) serum creatinine was 71 ± 20 mL/min/1.73m

conclusionsHigher levels of physical activity are associated with improved renal recovery after 6- months following an episode of stage 3 AKI. A future randomised controlled trial is feasible and would be required to confirm these initial findings.

Indexed as

Acute Kidney InjuryAftercareCreatinineExerciseFeasibility StudiesGlomerular Filtration RateHumansPatient DischargeRetrospective StudiesCreatinineAcute kidney injuryPhysical activityRenal recovery

Identifiers

PMID35410183
PMCPMC9004179
OpenAlexW4223610822

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.