Evidence map›Paper›PMID 35410141›Full record

ArticleBMC nephrology2022

Minimal change disease associated with gastrointestinal stromal tumor accompanied by significantly elevated serum IgE level: a case report.

Chun-Yang Yu, Jie Liu, Chang-Hai Qi, Zhen-Yu Wu, Yue-Fei Xiao, Xue-Guang Zhang

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Chun-Yang YuDepartment of Nephrology, Aerospace Center Hospital, Beijing, 100049, China.
Jie LiuHealth Management Center, Aerospace General Hospital, Beijing, China.
Chang-Hai QiDepartment of Pathology, Aerospace Center Hospital, Beijing, China.
Zhen-Yu WuDepartment of Hepatological Surgery, Aerospace Center Hospital, Beijing, China.
Yue-Fei XiaoDepartment of Nephrology, Aerospace Center Hospital, Beijing, 100049, China. xyf01_2012@163.com.
Xue-Guang ZhangDepartment of Nephrology, Capital Medical University Electric Teaching Hospital (State Grid Corporation of China Beijing Electric Power Hospital), Beijing, China. xg301301@163.com.
Aerospace Center Hospital · CNBeijing Aerospace General Hospital · CNState Grid Corporation of China (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMinimal change disease (MCD) is a common cause of the nephrotic syndrome. Several studies have shown an increased incidence of cancer in patients with MCD. However, there are no reports on the association between MCD and gastrointestinal stromal tumor (GIST). CASE PRESENTATION: We report a case of a 66-year-old female with severe nephrotic syndrome and concomitant duodenal GIST. Immunoglobulin test showed a significant increase of IgE levels. The diagnosis of renal histopathology was MCD with subacute tubulointerstitial injury. The combination of preoperative Imatinib mesylate chemotherapy and tumor excision was accompanied by significant remission of proteinuria, and IgE level decreasing, without immunosuppressivetherapy.

conclusionsIt is the first case report that MCD was associated with GIST and elevated IgE level. Clinically, in patients with elevated IgE level associated with nephrotic syndrome, the possibility of tumor must be taken into account when allergic factors are excluded.

Indexed as

Gastrointestinal Stromal TumorsNephrosis, LipoidNephrotic SyndromeAgedFemaleHumansImmunoglobulin EKidneyImmunoglobulin Egastrointestinal stromal tumorImmunoglobulin EMinimal change disease

Identifiers

PMID35410141
PMCPMC8996523
OpenAlexW4223446174

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.