Evidence map›Paper›PMID 35409687›Full record

ArticleInternational journal of environmental research and public health2022

Antibiotic Use in Suspected and Confirmed COVID-19 Patients Admitted to Health Facilities in Sierra Leone in 2020-2021: Practice Does Not Follow Policy.

Ibrahim Franklyn Kamara, Ajay M V Kumar, Anna Maruta, Bobson Derrick Fofanah, Charles Kuria Njuguna, Steven Shongwe, Francis Moses, Sia Morenike Tengbe, Joseph Sam Kanu, Sulaiman Lakoh and 4 more

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Impact of the COVID-19 Pandemic on Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2025
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  20. Antibiotic resistance and consumption before and during the COVID-19 pandemic in Valle del Cauca, Colombia.Revista panamericana de salud publica = Pan American journal of public health · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ibrahim Franklyn KamaraWorld Health Organization, 21A-B Riverside, Off King Harman Road Freetown, Freetown 00232, Sierra Leone.ORCID 0000-0003-1454-4650
Ajay M V KumarInternational Union Against Tuberculosis and Lung Disease, 68 Boulevard Saint Michel, 75006 Paris, France.ORCID 0000-0003-1011-8531
Anna MarutaWorld Health Organization, 21A-B Riverside, Off King Harman Road Freetown, Freetown 00232, Sierra Leone.ORCID 0000-0002-6417-7273
Bobson Derrick FofanahWorld Health Organization, 21A-B Riverside, Off King Harman Road Freetown, Freetown 00232, Sierra Leone.ORCID 0000-0003-3276-8949
Charles Kuria NjugunaWorld Health Organization, 21A-B Riverside, Off King Harman Road Freetown, Freetown 00232, Sierra Leone.
Steven ShongweWorld Health Organization, 21A-B Riverside, Off King Harman Road Freetown, Freetown 00232, Sierra Leone.
Francis MosesMinistry of Health and Sanitation, 4th Floor, Youyi Building, Brookfields, Freetown 00232, Sierra Leone.ORCID 0000-0002-9490-6537
Sia Morenike TengbeMinistry of Health and Sanitation, 4th Floor, Youyi Building, Brookfields, Freetown 00232, Sierra Leone.ORCID 0000-0001-7287-4426
Joseph Sam KanuNational Disease Surveillance Program, Ministry of Health and Sanitation, Sierra Leone National Public Health Emergency Operations Centre, Cockerill, Wilkinson Road, Freetown 00232, Sierra Leone.ORCID 0000-0003-0799-6907
Sulaiman LakohMinistry of Health and Sanitation, 4th Floor, Youyi Building, Brookfields, Freetown 00232, Sierra Leone.ORCID 0000-0002-7639-0004
Alie H D MansarayCrops Division, Ministry of Agriculture and Forestry, Youyi Building, Brookfields, Freetown 00232, Sierra Leone.
Kalaiselvi SelvarajAll India Institute of Medicine Sciences, Nagpur 441108, India.
Mohammed KhogaliSpecial Program for Research and Training in Tropical Diseases (TDR), World Health Organization, Avenue Appia 20, 1211 Geneva, Switzerland.
Rony ZachariahSpecial Program for Research and Training in Tropical Diseases (TDR), World Health Organization, Avenue Appia 20, 1211 Geneva, Switzerland.ORCID 0000-0002-2915-9328

Funding

World Health Organization 001
6 · The paper itself

Abstract

Inappropriate use of antibiotics during the COVID-19 pandemic has the potential to increase the burden of antimicrobial resistance. In this study, we report on the prevalence of antibiotic use and its associated factors among suspected and confirmed COVID-19 patients admitted to 35 health facilities in Sierra Leone from March 2020-March 2021. This was a cross-sectional study using routinely collected patient data. Of 700 confirmed COVID-19 patients, 47% received antibiotics. The majority (73%) of the antibiotics belonged to the 'WATCH' group of antibiotics, which are highly toxic and prone to resistance. The most frequently prescribed antibiotics were azithromycin, ceftriaxone, amoxicillin, metronidazole, and amoxicillin-clavulanic acid. Antibiotic use was significantly higher in patients aged 25-34 years than in those with severe disease. Of 755 suspected COVID-19 patients, 61% received antibiotics, of which the majority (58%) belonged to the 'WATCH' category. The most frequently prescribed antibiotics were ceftriaxone, metronidazole, azithromycin, ciprofloxacin, and amoxycillin. The prevalence of antibiotic use among suspected and confirmed COVID-19 patients admitted to healthcare facilities in Sierra Leone was high and not in line with national and WHO case management guidelines. Training of health care providers, strengthening of antimicrobial stewardship programs, and microbiological laboratory capacity are urgently needed.

Indexed as

COVID-19COVID-19 Drug TreatmentAnti-Bacterial AgentsAzithromycinCeftriaxoneCross-Sectional StudiesHealth FacilitiesHumansMetronidazolePandemicsPolicySierra LeoneAnti-Bacterial AgentsAzithromycinCeftriaxoneMetronidazoleantibiotic useantimicrobial resistanceantimicrobial stewardshipAWaRe classificationCOVID-19operational researchSierra LeoneSORT IT

Identifiers

PMID35409687
PMCPMC8998021

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.