Evidence map›Paper›PMID 35409574›Full record

ArticleInternational journal of environmental research and public health2022

Laminar Necrosis and Hypoxic Damage of the Placenta: A Case-Control Study.

Katia Mangialardi, Margherita Fanelli, Gerardo Cazzato, Andrea Marzullo, Maria Elisabetta Baldassarre, Antonella Vimercati, Leonardo Resta

Abstract read
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Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Katia MangialardiDepartment of Emergency and Organ Transplantation (DETO), Section of Pathology, School of Medicine University of Bari "Aldo Moro", 70124 Bari, Italy.
Margherita FanelliDepartment of Interdisciplinary Medicine, Medical Statistic, School of Medicine University of Bari "Aldo Moro", 70124 Bari, Italy.ORCID 0000-0002-0128-9745
Gerardo CazzatoDepartment of Emergency and Organ Transplantation (DETO), Section of Pathology, School of Medicine University of Bari "Aldo Moro", 70124 Bari, Italy.ORCID 0000-0003-0325-4316
Andrea MarzulloDepartment of Emergency and Organ Transplantation (DETO), Section of Pathology, School of Medicine University of Bari "Aldo Moro", 70124 Bari, Italy.
Maria Elisabetta BaldassarreDepartment of Biomedical Sciences and Human Oncology, Neonatology and Neonatal Intensive Care Unit, School of Medicine, University of Bari "Aldo Moro", 70124 Bari, Italy.ORCID 0000-0003-0590-6664
Antonella VimercatiDepartment of Biomedical Sciences and Human Oncology, Gynecologic and Obstetrics Clinic, School of Medicine, University of Bari "Aldo Moro", 70124 Bari, Italy.ORCID 0000-0002-9862-1619
Leonardo RestaDepartment of Emergency and Organ Transplantation (DETO), Section of Pathology, School of Medicine University of Bari "Aldo Moro", 70124 Bari, Italy.ORCID 0000-0003-4335-4776

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study is to verify the role of laminar necrosis (LN) in the diagnosis of hypoxic damage of the placenta. This is a retrospective case-control study in which 50 cases with laminar necrosis were compared with 100 gestational age-matched controls without laminar necrosis in a 1:2 ratio. The parameters analyzed were: the presence of other placental lesions, obstetric characteristics and neonatal outcome. For each of the 50 cases, the area affected by the lesion was detected, and the lesions were classified into three groups based on the morphology and time of onset of the lesion in order to understand whether these characteristics of the lesion had a clinical-pathology. The results showed that including the search for LN among placental lesions generally examined is useful to guide the pathologist in the diagnosis of placental dysfunction of hypoxic origin.

Indexed as

PlacentaPlacenta DiseasesCase-Control StudiesFemaleHumansHypoxiaInfant, NewbornNecrosisPregnancyPregnancy OutcomeRetrospective Studieshypoxic damagelaminar necrosisplacentaplacental dysfunctionplacental lesionspregnancy outcome

Identifiers

PMID35409574
PMCPMC8997949

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